Items where Subject is "protein tyrosine phosphatase"

A

Andersen, J. N., Jansen, P. G., Echwald, S. M., Mortensen, O. H., Fukada, T., Del Vecchio, R., Tonks, N. K., Moller, N. P. (January 2004) A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage. FASEB J, 18 (1). pp. 8-30. ISSN 1530-6860 (Electronic)

Andersen, J. N., Mortensen, O. H., Peters, G. H., Drake, P. G., Iversen, L. F., Olsen, O. H., Jansen, P. G., Andersen, H. S., Tonks, N. K., Moller, N. P. H. (November 2001) Structural and evolutionary relationships among protein tyrosine phosphatase domains. Molecular and Cellular Biology, 21 (21). pp. 7117-7136. ISSN 0270-7306

Andersen, J. N., Tonks, N. K. (2004) Protein tyrosine phosphatase-based therapeutics- lessons from PTP1B. In: Protein phosphatases. Topics in current genetics, 5 . Springer-Verlag, Berlin, pp. 201-230. ISBN 3540205608

B

Baratte, B., Meijer, L., Galaktionov, K., Beach, D. (May 1992) Screening for antimitotic compounds using the cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2/cyclin Bcdc13 protein kinase. Anticancer Research, 12 (3). pp. 873-880. ISSN 0250-7005

Barford, D., Flint, A. J., Tonks, N. K. (March 1994) Crystal structure of human protein tyrosine phosphatase 1B. Science, 263 (5152). pp. 1397-1404.

Barford, D., Jia, Z. C., Tonks, N. K. (December 1995) Protein tyrosine phosphatases take off. Nature Structural Biology, 2 (12). pp. 1043-1053. ISSN 1072-8368

Barford, D., Keller, J. C., Flint, A. J., Tonks, N. K. (June 1994) Purification and crystallization of the catalytic domain of human protein tyrosine phosphatase 1B expressed in Escherichia coli. Journal of Molecular Biology, 239 (5). pp. 726-730. ISSN 0022-2836

Bartlet-Jones, M., Jeffery, W. A., Hansen, H. F., Pappin, D. J. C. (1995) The use of a volatile N-terminal degradation reagent for rapid, high-sensitivity sequence analysis of peptides by generation of sequence ladders. In: Techniques in Protein Chemistry. Academic Press, pp. 3-11. ISBN 1080-8914

Barton, G. J., Cohen, P. T. W., Barford, D. (February 1994) Conservation Analysis and Structure Prediction of the Protein Serine/Threonine Phosphatases - Sequence Similarity with Diadenosine Tetraphosphatase from Escherichia-Coli Suggests Homology to the Protein Phosphatases. European Journal of Biochemistry, 220 (1). pp. 225-237. ISSN 0014-2956

Bianchi, C., Sellke, F. W., Del Vecchio, R. L., Tonks, N. K., Neel, B. G. (April 1999) Receptor-type protein-tyrosine phosphatase mu is expressed in specific vascular endothelial beds in vivo. Experimental Cell Research, 248 (1). pp. 329-338. ISSN 0014-4827

Boivin, B., Chaudhary, F., Dickinson, B. C., Haque, A., Pero, S. C., Chang, C. J., Tonks, N. K. (November 2013) Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein mediated mammary epithelial cell motility. Journal of Biological Chemistry, 288 (52). pp. 36926-36935. ISSN 00219258 (ISSN)

Boivin, B., Tonks, N. K. (2010) Analysis of the redox regulation of protein tyrosine phosphatase superfamily members utilizing a cysteinyl-labeling assay. In: Thiol Redox Transitions in Cell Signaling, Part B: Cellular Localization and Signaling. Methods in Enzymology, 474 . Elsevier Academic Press Inc, San Diego, pp. 35-50. ISBN 0076-6879978-0-12-381003-8

Boivin, B., Zhang, S. H., Arbiser, J. L., Zhang, Z.-Y., Tonks, N. K. (July 2008) A modified cysteinyl-labeling assay reveals reversible oxidation of classical and dual specificity phosphatases in angiomyolipoma cells. Proc Natl Acad Sci U S A, 105 (29). pp. 9959-9964.

Bonham, ChristopherA, Mandati, Vinay, Singh, RakeshK, Pappin, DarrylJ, Tonks, NicholasK (March 2023) Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks. Journal of Biological Chemistry. p. 104582. ISSN 0021-9258

Brady-Kalnay, S. M., Flint, A. J., Tonks, N. K. (August 1993) Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation. Journal of Cell Biology, 122 (4). pp. 961-972. ISSN 0021-9525

Brady-Kalnay, S. M., Mourton, T., Nixon, J. P., Pietz, G. E., Kinch, M., Chen, H. Y., Brackenbury, R., Rimm, D. L., Del Vecchio, R. L., Tonks, N. K. (April 1998) Dynamic interaction of PTP mu with multiple cadherins in vivo. Journal of Cell Biology, 141 (1). pp. 287-296. ISSN 0021-9525

Brady-Kalnay, S. M., Rimm, D. L., Tonks, N. K. (August 1995) Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo. Journal of Cell Biology, 130 (4). pp. 977-986. ISSN 0021-9525

Brady-Kalnay, S. M., Rimm, D. L., Tonks, N. K. (November 1995) The receptor protein-tyrosine-phosphatase PTP-mu associates with cadherins and catenins. Molecular Biology of the Cell, 6. p. 676. ISSN 1059-1524

Brady-Kalnay, S. M., Tonks, N. K. (November 1994) Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu. Journal of Biological Chemistry, 269 (45). pp. 28472-28477. ISSN 0021-9258

Brady-Kalnay, S. M., Tonks, N. K. (October 1995) Protein tyrosine phosphatases as adhesion receptors. Current Opinion in Cell Biology, 7 (5). pp. 650-657. ISSN 0955-0674

Brady-Kalnay, S. M., Tonks, N. K. (March 1994) Protein tyrosine phosphatases: from structure to function. Trends Cell Biol, 4 (3). pp. 73-6. ISSN 0962-8924 (Print)

Brady-Kalnay, S. M., Tonks, N. K. (November 1993) Purification and characterization of the human protein tyrosine phosphatase, PTP mu, from a baculovirus expression system. Molecular and Cellular Biochemistry, 128. pp. 131-141. ISSN 0300-8177

Bukczynska, P., Klingler-Hoffmann, M., Mitchelhill, K. I., Lam, M. H. C., Ciccomancini, M., Tonks, N. K., Sarcevic, B., Kemp, B. E., Tiganis, T. (June 2004) The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis. Biochemical Journal, 380. pp. 939-949. ISSN 0264-6021

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Charbonneau, H., Tonks, N. K. (1992) 1002 Protein Phosphatases? Annual Review of Cell Biology, 8. pp. 463-493. ISSN 0743-4634

Charles, C. H., Sun, H., Lau, L. F., Tonks, N. K. (June 1993) The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 90 (11). pp. 5292-5296. ISSN 0027-8424

Chaudhary, F., Lucito, R., Tonks, N. K. (October 2014) Missing-in-Metastasis regulates cell motility and invasion via PTPdelta-mediated changes in SRC activity. Biochemical Journal, 465 (1). pp. 89-101. ISSN 0264-6021

Chen, H. H., Luche, R., Wei, B., Tonks, N. K. (October 2004) Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2. J Biol Chem, 279 (40). pp. 41404-13. ISSN 0021-9258 (Print)

Cool, D. E., Andreassen, P. R., Tonks, N. K., Krebs, E. G., Fischer, E. H., Margolis, R. L. (June 1992) Cytokinetic failure and asynchronous nuclear division in BHK cells overexpressing a truncated protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 89 (12). pp. 5422-5426. ISSN 0027-8424

D

Dagnell, M., Frijhoff, J., Pader, I., Augsten, M., Boivin, B., Xu, J., Mandal, P. K., Tonks, N. K., Hellberg, C., Conrad, M., Arnér, E. S. J., Östman, A. (August 2013) Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-ß receptor tyrosine kinase signaling. Proceedings of the National Academy of Sciences of the United States of America, 110 (33). pp. 13398-13403. ISSN 00278424

Del Vecchio, R. L., Tonks, N. K. (January 2005) The conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase mu. J Biol Chem, 280 (2). pp. 1603-12. ISSN 0021-9258 (Print)

Delvecchio, R. L., Tonks, N. K. (July 1994) Characterization of two structurally related Xenopus laevis protein tyrosine phosphatases with homology to lipid-binding proteins. Journal of Biological Chemistry, 269 (30). pp. 19639-19645. ISSN 0021-9258

Demetrick, D. J., Beach, D. H. (October 1993) Chromosome mapping of human CDC25A and CDC25B phosphatases. Genomics, 18 (1). pp. 144-7. ISSN 0888-7543 (Print)

F

Fan, G., Aleem, S., Yang, M., Miller, W. T., Tonks, N. K. (June 2015) Protein Tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and BRK. Journal of Biological Chemistry, 290 (26). pp. 15934-15947. ISSN 0021-9258

Fan, G., Lin, G., Lucito, R., Tonks, N. K. (June 2013) Protein Tyrosine Phosphatase 1B Antagonized Signaling by IGF-1 Receptor and BRK/PTK6 in Ovarian Cancer Cells. Journal of Biological Chemistry, 288 (34). pp. 24923-29434. ISSN 0021-9258

Fischer, E. H., Charbonneau, H., Cool, D. E., Tonks, N. K. (1992) Tyrosine phosphatases and their possible interplay with tyrosine kinases. Ciba Foundation Symposia, 164. pp. 132-144. ISSN 0300-5208

Flint, A. J., Gebbink, M. F., Franza, B. R., Hill, D. E., Tonks, N. K. (May 1993) Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation. Embo Journal, 12 (5). pp. 1937-1946. ISSN 0261-4189

Flint, A. J., Tiganis, T., Barford, D., Tonks, N. K. (March 1997) Development of ''substrate-trapping'' mutants to identify physiological substrates of protein tyrosine phosphatases. Proceedings of the National Academy of Sciences of the United States of America, 94 (5). pp. 1680-1685. ISSN 0027-8424

Fukada, T., Tonks, N. K. (February 2003) Identification of YB-1 as a regulator of PTP1B expression: implications for regulation of insulin and cytokine signaling. Embo Journal, 22 (3). pp. 479-493. ISSN 0261-4189

Fukada, T., Tonks, N. K. (July 2001) The reciprocal role of Egr-1 and Sp family proteins in regulation of the PTP1B promoter in response to the p210 Bcr-Abl oncoprotein-tyrosine kinase. Journal of Biological Chemistry, 276 (27). pp. 25512-25519. ISSN 0021-9258

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Galaktionov, K., Beach, D. (December 1991) Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. Cell, 67 (6). pp. 1181-94. ISSN 0092-8674 (Print)0092-8674 (Linking)

Galic, S., Hauser, C., Kahn, B. B., Haj, F. G., Neel, B. G., Tonks, N. K., Tiganis, T. (January 2005) Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP. Molecular and Cellular Biology, 25 (2). pp. 819-829. ISSN 0270-7306

Galic, S., Klingler-Hoffmann, M., Fodero-Tavoletti, M. T., Puryer, M. A., Meng, T. C., Tonks, N. K., Tiganis, T. (March 2003) Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP. Molecular and Cellular Biology, 23 (6). pp. 2096-2108. ISSN 0270-7306

Garton, A. J., Burnham, M. R., Bouton, A. H., Tonks, N. K. (August 1997) Association of PTP-PEST with the SH3 domain of p130(cas); a novel mechanism of protein tyrosine phosphatase substrate recognition. Oncogene, 15 (8). pp. 877-885. ISSN 0950-9232

Garton, A. J., Flint, A. J., Tonks, N. K. (November 1996) Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST. Molecular and Cellular Biology, 16 (11). pp. 6408-6418. ISSN 0270-7306

Garton, A. J., Tonks, N. K. (August 1994) PTP-PEST: a protein tyrosine phosphatase regulated by serine phosphorylation. Embo Journal, 13 (16). pp. 3763-3771. ISSN 0261-4189

Garton, A. J., Tonks, N. K. (February 1999) Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST. Journal of Biological Chemistry, 274 (6). pp. 3811-3818. ISSN 0021-9258

Gutch, M. J., Flint, A. J., Keller, J., Tonks, N. K., Hengartner, M. O. (February 1998) The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development. Genes & Development, 12 (4). pp. 571-585. ISSN 0890-9369

H

Hao, L. N., Tiganis, T., Tonks, N. K., Charbonneau, H. (November 1997) The noncatalytic C-terminal segment of the T cell protein tyrosine phosphatase regulates activity via an intramolecular mechanism. Journal of Biological Chemistry, 272 (46). pp. 29322-29329. ISSN 0021-9258

Harrington, R. J., Gutch, M. J., Hengartner, M. O., Tonks, N. K., Chisholm, A. D. (May 2002) The C-elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis. Development, 129 (9). pp. 2141-2153. ISSN 0950-1991

Hinton, S. D., Yang, D. Z., Eckberg, W. R. (October 2003) Protein tyrosine phosphatases in Chaetopterus egg activation. Development Growth & Differentiation, 45 (5-6). pp. 405-415. ISSN 0012-1592

Hoffmann, K. M. V., Tonks, N. K., Barford, D. (October 1997) The crystal structure of domain 1 of receptor protein-tyrosine phosphatase mu. Journal of Biological Chemistry, 272 (44). pp. 27505-27508. ISSN 0021-9258

Hyun, S. W., Sui, X., Del Vecchio, R. L., Tonks, N. K., Passaniti, A., Goldblum, S. E. (November 2004) Protein tyrosine phosphatase (PTP) mu regulates endothelial cell (EC) proliferation, adhesion and migration. Molecular Biology of the Cell, 15. 226A-226A. ISSN 1059-1524

J

Jia, Z. C., Barford, D., Flint, A. J., Tonks, N. K. (June 1995) Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268 (5218). pp. 1754-1758. ISSN 0036-8075

K

Kontaridis, M. I., Eminaga, S., Fornaro, M., Zito, C. I., Sordella, R., Settleman, J., Bennett, A. M. (June 2004) SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Molecular and Cellular Biology, 24 (12). pp. 5340-52. ISSN 0270-7306

Krishnan, N. (November 2012) Regulation of Protein Tyrsoine Phosphatase by Hydrogen Sulfide. Free Radical Biology and Medicine, 53 (Supple). S33-S33. ISSN 0891-5849

Krishnan, N., Bencze, G., Cohen, P., Tonks, N. K. (April 2013) The anti-inflammatory compound BAY 11-7082 is a potent inhibitor of Protein Tyrosine Phosphatases. FEBS Journal, 280 (12). pp. 2830-2841. ISSN 1742-464X

Krishnan, N., Bonham, C. A., Rus, I. A., Shrestha, O. K., Gauss, C. M., Haque, A., Tocilj, A., Joshua-Tor, L., Tonks, N. K. (January 2018) Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development. Nat Commun, 9 (1). p. 283. ISSN 2041-1723

Krishnan, N., Fu, C., Pappin, D. J., Tonks, N. K. (2011) H2S-induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response. Science Signaling, 4 (203). ISSN 19450877 (ISSN)

Krishnan, N., Konidaris, K. F., Gasser, G., Tonks, N. K. (February 2018) A potent, selective and orally bioavailable inhibitor of the protein tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models. J Biol Chem, 293 (5). pp. 1517-1525. ISSN 0021-9258

Krishnan, N., Koveal, D., Miller, D. H., Xue, B., Akshinthala, S. D., Kragelj, J., Jensen, M. R., Gauss, C. M., Page, R., Blackledge, M., Muthuswamy, S. K., Peti, W., Tonks, N. K. (May 2014) Targeting the disordered C terminus of PTP1B with an allosteric inhibitor. Nature Chemical Biology, 10 (7). pp. 558-566. ISSN 15524450

Krishnan, N., Krishnan, K., Connors, C. R., Choy, M. S., Page, R., Peti, W., Van Aelst, L., Shea, S. D., Tonks, N. K. (July 2015) PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest, 125 (8). pp. 3163-3177. ISSN 1558-8238 (Electronic)0021-9738 (Linking)

Krishnan, Navasona, Tonks, Nicholas K. (August 2015) Anxious moments for the protein tyrosine phosphatase PTP1B. Trends in Neurosciences, 38 (8). pp. 462-465. ISSN 0166-2236

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La Montagne, K. R., Flint, A. J., Franza, B. R., Pendergast, A. M., Tonks, N. K. (May 1998) Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo. Molecular and Cellular Biology, 18 (5). pp. 2965-2975. ISSN 0270-7306

La Montagne, K. R., Pendergast, A. M., Franza, B. R., Tonks, N. K. (January 1995) Enhanced expression of a protein-tyrosine phosphatase in cells expressing P210BCR/ABL. Journal of Cellular Biochemistry. p. 65. ISSN 0730-2312

LaMontagne, K. R., Hannon, G., Tonks, N. K. (November 1998) Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells. Proceedings of the National Academy of Sciences of the United States of America, 95 (24). pp. 14094-14099. ISSN 0027-8424

Labbe, D. P., Uetani, N., Vinette, V., Lessard, L., Aubry, I., Migon, E., Sirois, J., Haigh, J., Begin, L. R., Trotman, L. C., Paquet, M., Tremblay, M. L. (June 2016) PTP1B deficiency enables the ability of a high fat diet to drive the invasive character of PTEN-deficient prostate cancers. Cancer Res, 76 (11). pp. 3130-3135. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Lai, C. C., Boguski, M., Broek, D., Powers, S. (March 1993) Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins. Mol Cell Biol, 13 (3). pp. 1345-52. ISSN 0270-7306 (Print)0270-7306

Lam, M. H. C., Michell, B. J., Fodero-Tavoletti, M. T., Kemp, B. E., Tonks, N. K., Tiganis, T. (October 2001) Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase TCPTP. Journal of Biological Chemistry, 276 (40). pp. 37700-37707. ISSN 0021-9258

Lammers, R., Bossenmaier, B., Cool, D. E., Tonks, N. K., Schlessinger, J., Fischer, E. H., Ullrich, A. (October 1993) Differential activities of protein tyrosine phosphatases in intact cells. Journal of Biological Chemistry, 268 (30). pp. 22456-22462. ISSN 0021-9258

Lavoie, C., Chevet, E., Roy, L., Tonks, N. K., Fazel, A., Posner, B. I., Paiement, J., Bergeron, J. J. M. (December 2000) Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro. Proceedings of the National Academy of Sciences of the United States of America, 97 (25). pp. 13637-13642. ISSN 0027-8424

Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., Parsons, R. (March 1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 275 (5308). pp. 1943-7. ISSN 0036-8075 (Print)

Lin, G., Aranda, V., Muthuswamy, S. K., Tonks, N. K. (July 2011) Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'. Genes & Development, 25 (13). pp. 1412-1425. ISSN 0890-9369

Lindtner, C., Scherer, T., Zielinski, E., Filatova, N., Fasshauer, M., Tonks, N. K., Puchowicz, M., Buettner, C. (January 2013) Binge Drinking Induces Whole-Body Insulin Resistance by Impairing Hypothalamic Insulin Action. Science Translational Medicine, 5 (170). ISSN 1946-6234

Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B. J., Skiba, B., Ooms, L. M., Stepto, N., Wu, B., Mitchell, C. A., Tonks, N. K., Watt, M. J., Febbraio, M. A., Crack, P. J., Andrikopoulos, S., Tiganis, T. (October 2009) Reactive Oxygen Species Enhance Insulin Sensitivity. Cell Metabolism, 10 (4). pp. 260-272.

Londhe, A. D., Bergeron, A., Curley, S. M., Zhang, F., Rivera, K. D., Kannan, A., Coulis, G., Rizvi, S. H. M., Kim, S. J., Pappin, D. J., Tonks, N. K., Linhardt, R. J., Boivin, B. (December 2019) Regulation of PTP1B activation through disruption of redox-complex formation. Nat Chem Biol, 16 (2). pp. 122-125. ISSN 1552-4450

Londhe, Avinash, Rizvi, Syed Husain Mustafa, Rivera, Keith, Kim, Seung Jun, Pappin, Darryl, Boivin, Ben, Zhang, Fuming, Linhardt, Robert (November 2020) Characterization of Peptide Activators of Protein Tyrosine Phosphatase 1B. In: 27th Annual Conference of the Society-for-Redox-Biology-and-Medicine (SfRBM).

Lou, Y.-W., Chen, Y.-Y., Hsu, S.-F., Chen, R.-K., Lee, C.-L., Khoo, K.-H., Tonks, N. K., Meng, T.-C. (January 2008) Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells. FEBS Journal, 275 (1). pp. 69-88.

M

MacKintosh, C., Garton, A. J., McDonnell, A., Barford, D., Cohen, P. T. W., Tonks, N. K., Cohen, P. (November 1996) Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation. Febs Letters, 397 (2-3). pp. 235-238. ISSN 0014-5793

McGuire, M. C., Fields, R. M., Nyomba, B. L., Raz, I., Bogardus, C., Tonks, N. K., Sommercorn, J. (July 1991) Abnormal regulation of protein tyrosine phosphatase activities in skeletal muscle of insulin-resistant humans. Diabetes, 40 (7). pp. 939-942. ISSN 0012-1797

Meng, T. C., Buckley, D. A., Galic, S., Tiganis, T., Tonks, N. K. (September 2004) Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J Biol Chem, 279 (36). pp. 37716-25. ISSN 0021-9258 (Print)

Meng, T. C., Fukada, T., Tonks, N. K. (February 2002) Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Molecular Cell, 9 (2). pp. 387-399. ISSN 1097-2765

Meng, T. C., Hsu, S. F., Tonks, N. K. (January 2005) Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo. Methods, 35 (1). pp. 28-36. ISSN 1046-2023

Meng, T. C., Tonks, N. K. (2003) Analysis of the regulation of protein tyrosine phosphatases in vivo by reversible oxidation. In: Protein Phosphatases. Methods in Enzymology, 366 . Academic Press Inc, San Diego, pp. 304-318. ISBN 0076-6879

Mondol, A. S., Tonks, N. K., Kamata, T. (February 2014) Nox4 redox regulation of PTP1B contributes to the proliferation and migration of glioblastoma cells by modulating tyrosine phosphorylation of coronin-1C. Free Radical Biology and Medicine, 67. pp. 285-91. ISSN 0891-5849

Moskal, D., Tonks, N. K., Lucito, R. (August 2015) Alteration of the protein tyrosine phosphatome in cancer. Cancer Research, 75 (Supple). Abstract 1933. ISSN 0008-5472

Myers, M. P., Andersen, J. N., Cheng, A., Tremblay, M. L., Horvath, C. M., Parisien, J. P., Salmeen, A., Barford, D., Tonks, N. K. (December 2001) TYK2 and JAR2 are substrates of protein-tyrosine phosphatase 1B. Journal of Biological Chemistry, 276 (51). pp. 47771-47774. ISSN 0021-9258

Myers, M. P., Pass, I., Batty, I. H., Van der Kaay, J., Stolarov, J. P., Hemmings, B. A., Wigler, M. H., Downes, C. P., Tonks, N. K. (November 1998) The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A, 95 (23). pp. 13513-8. ISSN 0027-8424 (Print)

Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., Tonks, N. K. (August 1997) P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A, 94 (17). pp. 9052-7. ISSN 0027-8424 (Print)

Myers, M. P., Tonks, N. K. (December 1997) PTEN: Sometimes taking it off can be better than putting it on. American Journal of Human Genetics, 61 (6). pp. 1234-1238. ISSN 0002-9297

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Neel, B. G., Tonks, N. K. (April 1997) Protein tyrosine phosphatases in signal transduction. Current Opinion in Cell Biology, 9 (2). pp. 193-204. ISSN 0955-0674

Nelson, K., Meng, T. C., Tonks, N., Melendez, J. A. (2002) Mitochondrial H2O2 enhances matrix metalloproteinase expression by protein tyrosine phosphatase inactivation. Free Radical Biology and Medicine, 33. S355-S355. ISSN 0891-5849

O

Ostman, A., Yang, Q., Tonks, N. K. (October 1994) Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density. Proceedings of the National Academy of Sciences of the United States of America, 91 (21). pp. 9680-9684. ISSN 0027-8424

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Palka, H. L., Park, M., Tonks, N. K. (February 2003) Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1. Journal of Biological Chemistry, 278 (8). pp. 5728-35. ISSN 0021-9258

Pannifer, A. D. B., Flint, A. J., Tonks, N. K., Barford, D. (April 1998) Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by X-ray crystallography. Journal of Biological Chemistry, 273 (17). pp. 10454-10462. ISSN 0021-9258

Park, C. Y., La Montagne, K. R., Tonks, N. K., Hayman, M. J. (October 1996) Cloning and expression of the chicken protein tyrosine phosphatase SH-PTP2. Gene, 177 (1-2). pp. 93-97. ISSN 0378-1119

Potts, M., Sun, H., Mockaitis, K., Kennelly, P. J., Reed, D., Tonks, N. K. (April 1993) A protein-tyrosine/serine phosphatase encoded by the genome of the cyanobacterium Nostoc commune UTEX 584. Journal of Biological Chemistry, 268 (11). pp. 7632-7635. ISSN 0021-9258

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Qian, Zhe, Song, Dongyan, Ipsaro, Jonathan J, Bautista, Carmelita, Joshua-Tor, Leemor, Yeh, Johannes T-H, Tonks, Nicholas K (September 2023) Manipulating PTPRD function with ectodomain antibodies. Genes and Development. ISSN 0890-9369

Qian, M., Pan, G., Sun, L., Feng, C., Xie, Z., Tully, T., Zhong, Y. (2007) Receptor-like tyrosine phosphatase PTP10D is required for long-term memory in Drosophila. Journal of Neuroscience, 27 (16). pp. 4396-4402. ISSN 02706474 (ISSN)

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Ramachandran, C., Aebersold, R., Tonks, N. K., Pot, D. A. (May 1992) Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases. Biochemistry, 31 (17). pp. 4232-4238. ISSN 0006-2960

Ramesh, M., Krishnan, N., Muthuswamy, S. K., Tonks, N. K. (April 2015) A Novel Phosphatidic Acid-Protein Tyrosine Phosphatase D2 Axis is Essential for ERBB2 Signaling in Mammary Epithelial Cells. Journal of Biological Chemistry, 290 (15). pp. 9646-9659. ISSN 0021-9258

Ruzinova, M. B., Schoer, R. A., Gerald, W., Egan, J. E., Pandolfi, P. P., Rafii, S., Manova, K., Mittal, V., Benezra, R. (October 2003) Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell, 4 (4). pp. 277-289. ISSN 1535-6108

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Salmeen, A., Andersen, J. N., Myers, M. P., Meng, T. C., Hinks, J. A., Tonks, N. K., Barford, D. (June 2003) Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate. Nature, 423 (6941). pp. 769-773. ISSN 0028-0836

Salmeen, A., Andersen, J. N., Myers, M. P., Tonks, N. K., Barford, D. (December 2000) Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B. Molecular Cell, 6 (6). pp. 1401-1412. ISSN 1097-2765

Schwertassek, U., Haque, A., Krishnan, N., Greiner, R., Weingarten, L., Dick, T. P., Tonks, N. K. (June 2014) Reactivation of oxidized PTP1B and PTEN by Thioredoxin 1. Febs Journal, 281 (16). pp. 3545-3558. ISSN 1742-464X

Shen, Y., Luche, R., Wei, B., Gordon, M. L., Diltz, C. D., Tonks, N. K. (November 2001) Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1. Proceedings of the National Academy of Sciences of the United States of America, 98 (24). pp. 13613-13618. ISSN 0027-8424

Shual, K., Ziemiecki, A., Wilks, A. F., Harpur, A. G., Sadowski, H. B., Gilman, M. Z., Darnell, J. E. (December 1993) Polypeptide Signaling to the Nucleus through Tyrosine Phosphorylation of Jak and Stat Proteins. Nature, 366 (6455). pp. 580-583. ISSN 0028-0836

Stover, D. R., Charbonneau, H., Tonks, N. K., Walsh, K. A. (September 1991) Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells. Proceedings of the National Academy of Sciences of the United States of America, 88 (17). pp. 7704-7707. ISSN 0027-8424

Sui, X., Hyun, S. W., Kiser, T. D., Del Vecchio, R. L., Tonks, N. K., Passaniti, A., Goldblum, S. E. (November 2004) Receptor protein tyrosine phosphatase (PTP) mu regulates the endothelial paracellular pathway. Molecular Biology of the Cell, 15. 428A-428A. ISSN 1059-1524

Sui, X., Kiser, T. D., Del Vecchio, R. L., Young, B. A., Gregoryev, D., Garcia, J. G. N., Tonks, N. K., Goldblum, S. E. (November 2001) PTP mu regulates the tyrosine phosphorylation state of VE-cadherin and the pulmonary microvascular endothelial paracellular pathway. Molecular Biology of the Cell, 12. 158A-158A. ISSN 1059-1524

Sui, X. F., Kiser, T. D., Hyun, S. W., Angelini, D. J., Del Vecchio, R. L., Young, B. A., Hasday, J. D., Romer, L. H., Passaniti, A., Tonks, N. K., Goldblum, S. E. (April 2005) Receptor protein tyrosine phosphatase mu regulates the paracellular pathway in human lung microvascular endothelia. American Journal of Pathology, 166 (4). pp. 1247-1258. ISSN 0002-9440

Sun, H., Tonks, N. K. (November 1994) The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends in Biochemical Sciences, 19 (11). pp. 480-485. ISSN 0968-0004

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Tabet, F., Schiffrin, E. L., Callera, G., He, Y., Yao, G., Ostman, A., Kappert, K., Tonks, N. K., Touyz, R. M. (July 2008) Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR. Circ Res, 103 (2). pp. 149-158.

Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Lees, E. K., Tonks, N. K., Mody, N., Wilson, H. M., Delibegovic, M. (March 2017) Genetic deletion and pharmacological inhibition of macrophage protein tyrosine phosphatase 1B (PTP1B) improves global glucose and lipid homeostasis and protects against atherosclerotic plaque formation in mouse models of atherosclerosis. Diabetic Medicine, 34 (Supple). pp. 26-27. ISSN 0742-3071

Tiganis, T., Bennett, A. M., Ravichandran, K. S., Tonks, N. K. (March 1998) Epidermal growth factor receptor and the adaptor protein p52(Shc) are specific substrates of T-cell protein tyrosine phosphatase. Molecular and Cellular Biology, 18 (3). pp. 1622-1634. ISSN 0270-7306

Tiganis, T., Flint, A. J., Adam, S. A., Tonks, N. K. (August 1997) Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97. Journal of Biological Chemistry, 272 (34). pp. 21548-21557. ISSN 0021-9258

Tiganis, T., Kemp, B. E., Tonks, N. K. (September 1999) The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling. Journal of Biological Chemistry, 274 (39). pp. 27768-27775. ISSN 0021-9258

Tonks, Nicholas K (April 2023) Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow. IUBMB Life, 75 (4). pp. 337-352. ISSN 1521-6543

Tonks, N. (November 2012) HARNESSING REDOX REGULATION OF PROTEIN TYROSINE PHOSPHATASES. Free Radical Biology and Medicine, 53 (Supple). S3-S3. ISSN 0891-5849

Tonks, N., Krishnan, N. (2008) Regulation of Protein Tyrsoine Phosphatase by Hydrogen Sulphide. Free Radical Biology and Medicine, 45 (Suppl.). S18-S19. ISSN 0891-5849

Tonks, N., Krishnan, N. (2008) Unraveling the Mechanism of Redox Regulation in Protein Tyrosine Phosphatases. Free Radical Biology and Medicine, 45 (Suppl.). S62-S62. ISSN 0891-5849

Tonks, N., Lucito, R. (October 2014) Global assessment of the protein tyrosine phosphatome in cancer. Cancer Research, 74 (19). ISSN 0008-5472

Tonks, N. K. (March 2000) From structure to function of protein tyrosine phosphatases. Abstracts of Papers of the American Chemical Society, 219. U7-U7. ISSN 0065-7727

Tonks, N. K. (1998) From structure to function of protein tyrosine phosphatases. Naunyn-Schmiedebergs Archives of Pharmacology, 358 (1). R377-R377. ISSN 0028-1298

Tonks, N. K. (July 1997) From structure to function of protein tyrosine phosphatases. Faseb Journal, 11 (9). A1012-A1012. ISSN 0892-6638

Tonks, N. K. (July 2003) PTP1B: From the sidelines to the front lines! Febs Letters, 546 (1). pp. 140-148. ISSN 0014-5793

Tonks, N. K. (August 1991) Plague, pox and tyrosine dephosphorylation. Curr Biol, 1 (4). pp. 259-61.

Tonks, N. K. (April 2013) Protein Tyrosine Phosphatases: Critical Regulators of Signaling in Cancer. Faseb Journal, 27 (1). ISSN 0892-6638

Tonks, N. K. (January 2013) Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction. Febs Journal, 280 (2). pp. 346-378. ISSN 1742464X

Tonks, N. K. (April 1996) Protein tyrosine phosphatases and the control of the cellular signalling responses. Faseb Journal, 10 (6). P13-P13. ISSN 0892-6638

Tonks, N. K. (April 1994) Protein tyrosine phosphatases and the control of the cellular signalling responses. Faseb Journal, 8 (7). A1377-A1377. ISSN 0892-6638

Tonks, N. K. (November 2006) Protein tyrosine phosphatases: from genes, to function, to disease. Nat Rev Mol Cell Biol, 7 (11). pp. 833-46. ISSN 1471-0072 (Print)

Tonks, N. K. (June 2005) Redox redux: revisiting PTPs and the control of cell signaling. Cell, 121 (5). pp. 667-70. ISSN 0092-8674 (Print)

Tonks, N. K. (October 2007) The protein tyrosine phosphatase superfamily of enzymes. Toxicology Letters, 172 (Supple). S10-S11. ISSN 0378-4274

Tonks, N. K., Diltz, C. D., Fischer, E. H. (1991) Purification and assay of CD45: an integral membrane protein-tyrosine phosphatase. Methods in Enzymology, 201. pp. 442-451. ISSN 0076-6879

Tonks, N. K., Diltz, C. D., Fischer, E. H. (1991) Purification of protein-tyrosine phosphatases from human placenta. Methods in Enzymology, 201. pp. 427-442. ISSN 0076-6879

Tonks, N. K., Flint, A. J., Gebbink, M. F., Sun, H., Yang, Q. (1993) Signal transduction and protein tyrosine dephosphorylation. Adv Second Messenger Phosphoprotein Res, 28. pp. 203-10. ISSN 1040-7952 (Print)

Tonks, N. K., Muthuswamy, S. K. (March 2007) A Brake Becomes an Accelerator: PTP1B-A New Therapeutic Target for Breast Cancer. Cancer Cell, 11 (3). pp. 214-6. ISSN 1535-6108 (Print)

Tonks, N. K., Neel, B. G. (April 2001) Combinatorial control of the specificity of protein tyrosine phosphatases. Current Opinion in Cell Biology, 13 (2). pp. 182-195. ISSN 0955-0674

Tonks, N. K., Neel, B. G. (November 1996) From form to function: Signaling by protein tyrosine phosphatases. Cell, 87 (3). pp. 365-368. ISSN 0092-8674

Tonks, N. K., Yang, Q., Flint, A. J., Gebbink, M. F., Franza, B. R., Hill, D. E., Sun, H., Brady-Kalnay, S. M. (1992) Protein tyrosine phosphatases: the problems of a growing family. Cold Spring Harbor Symposia on Quantitative Biology, 57. pp. 87-94. ISSN 0091-7451

Tonks, N. K., Yang, Q., Guida, P. (1991) Structure, regulation, and function of protein tyrosine phosphatases. Cold Spring Harbor Symposia on Quantitative Biology, 56. pp. 265-273. ISSN 0091-7451

Tonks, N. K. (November 2012) Talk from Nick Tonks at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Y

Yang, M., Haase, A. D., Huang, F. K., Coulis, G., Rivera, K. D., Dickinson, B. C., Chang, C. J., Pappin, D. J., Neubert, T. A., Hannon, G. J., Boivin, B., Tonks, N. K. (August 2014) Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence. Mol Cell, 55 (5). pp. 782-790. ISSN 1097-2765

Yang, Q., Co, D., Sommercorn, J., Tonks, N. K. (March 1993) Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase. Journal of Biological Chemistry, 268 (9). pp. 6622-6628. ISSN 0021-9258

Yang, Q., Tonks, N. K. (July 1991) Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin. Proceedings of the National Academy of Sciences of the United States of America, 88 (14). pp. 5949-5953. ISSN 0027-8424

Z

Zander, N. F., Lorenzen, J. A., Cool, D. E., Tonks, N. K., Daum, G., Krebs, E. G., Fischer, E. H. (July 1991) Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system. Biochemistry, 30 (28). pp. 6964-6970. ISSN 0006-2960

Zhang, Jiali, Wang, Zuo, Zhang, Siwei, Chen, Yanxun, Xiong, Xuexue, Li, Xiaojuan, Tonks, Nicholas K., Fan, Gaofeng (June 2018) Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER. Cellular Signalling, 50. pp. 100-110. ISSN 0898-6568

Zhang, S., Fan, G., Hao, Y., Hammell, M., Wilkinson, J. E., Tonks, N. K. (October 2017) Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase. Genes Dev, 31 (19). pp. 1939-57. ISSN 0890-9369

Zhang, S. H., Eckberg, W. R., Yang, Q., Samatar, A. A., Tonks, N. K. (August 1995) Biochemical characterization of a human band 4.1-related protein-tyrosine phosphatase, PTPH1. Journal of Biological Chemistry, 270 (34). pp. 20067-20072. ISSN 0021-9258

Zhang, S. H., Kobayashi, R., Graves, P. R., Piwnica-Worms, H., Tonks, N. K. (October 1997) Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3 beta protein. Journal of Biological Chemistry, 272 (43). pp. 27281-27287. ISSN 0021-9258

Zhang, S. H., Liu, J. P., Kobayashi, R., Tonks, N. K. (June 1999) Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1. Journal of Biological Chemistry, 274 (25). pp. 17806-17812. ISSN 0021-9258

Zhang, S. H., Tonks, N. K. (December 1996) Phosphorylation-dependent association of band 4.1-related protein tyrosine phosphatase PTPH1 and 14-3-3B. Molecular Biology of the Cell, 7. p. 83. ISSN 1059-1524