Items where Subject is "tyrosine kinase"

Paper

Albers, C., Illert, A. L., Miething, C., Leischner, H., Thiede, M., Peschel, C., Duyster, J. (August 2011) An RNAi-based system for loss-of-function analysis identifies Raf1 as a crucial mediator of BCR-ABL - Driven leukemogenesis. Blood, 118 (8). pp. 2200-2210. ISSN 00064971 (ISSN)

Asztalos, Z., Baba, K., Yamamoto, D., Tully, T. (January 2007) The Fickle mutatation of a cytoplasmic tyrosine kinase effects sensitization but not dishabituation in Drosophila melanogaster. J Neurogenet, 21 (1). pp. 59-71. ISSN 0167-7063 (Print)

Bar-Sagi, D. (May 1994) The Sos (Son of Sevenless) Protein. Trends in Endocrinology and Metabolism, 5 (4). pp. 165-169. ISSN 1043-2760

Bell, D. W., Gore, I., Okimoto, R. A., Godin-Heymann, N., Sordella, R., Mulloy, R., Sharma, S. V., Brannigan, B. W., Mohapatra, G., Settleman, J., Haber, D. A. (December 2005) Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Nature Genetics, 37 (12). pp. 1315-6. ISSN 1061-4036

Birchmeier, C., Birnbaum, D., Waitches, G., Fasano, O., Wigler, M. H. (1986) Characterization of an activated human ros gene. Molecular & Cellular Biology, 6 (9). pp. 3109-3116.

Birchmeier, C., O'Neill, K., Riggs, M., Wigler, M. H. (1990) Characterization of Ros1 cDNA from a Human Glioblastoma Cell Line. Proceedings of the National Academy of Sciences of the United States of America, 87 (12). pp. 4799-4803.

Bivona, T. G., Hieronymus, H., Parker, J., Chang, K., Taron, M., Rosell, R., Moonsamy, P., Dahlman, K., Miller, V. A., Costa, C., Hannon, G. J., Sawyers, C. L. (March 2011) FAS and NF-kappa B signalling modulate dependence of lung cancers on mutant EGFR. Nature, 471 (7339). pp. 523-526. ISSN 0028-0836

Blanke, C. D., Rankin, C., Demetri, G. D., Ryan, C. W., von Mehren, M., Benjamin, R. S., Raymond, A. K., Bramwell, V. H., Baker, L. H., Maki, R. G., Tanaka, M., Hecht, J. R., Heinrich, M. C., Fletcher, C. D., Crowley, J. J., Borden, E. C. (February 2008) Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033. J Clin Oncol, 26 (4). pp. 626-32. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Boivin, B., Tonks, N. K. , Yang, M. (August 2010) Targeting the reversibly oxidized protein tyrosine phosphatase superfamily. Science Signaling, 3 (137).

Bolduc, F. V., Bell, K. G., Rosenfelt, C., Cox, H., Tully, T. (January 2010) Fragile x mental retardation 1 and filamin a interact genetically in Drosophila long-term memory. Front Neural Circuits, 3. p. 22. ISSN 1662-5110 (Electronic) 1662-5110 (Linking)

Brennand, K. J., Simone, A., Jou, J., Gelboin-Burkhart, C., Tran, N., Sangar, S., Li, Y., Mu, Y., Chen, G., Yu, D., McCarthy, S. E., Sebat, J., Gage, F. H. (May 2011) Modelling schizophrenia using human induced pluripotent stem cells. Nature, 473 (7346). 221 - 225. ISSN 00280836 (ISSN)

Broser, P., Grinevich, V., Osten, P., Sakmann, B., Wallace, D. J. (July 2008) Critical period plasticity of axonal arbors of layer 2/3 pyramidal neurons in rat somatosensory cortex: layer-specific reduction of projections into deprived cortical columns. Cerebral Cortex, 18 (7). pp. 1588-603. ISSN 1047-3211

Broser, P. J., Erdogan, S., Grinevich, V., Osten, P., Sakmann, B., Wallace, D. J. (March 2008) Automated axon length quantification for populations of labelled neurons. Journal of Neuroscience Methods, 169 (1). pp. 43-54. ISSN 0165-0270

Burgess, D. J., Doles, J., Zender, L., Xue, W., Ma, B., McCombie, W. R., Hannon, G. J., Lowe, S. W., Hemann, M. T. (July 2008) Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc Natl Acad Sci U S A, 105 (25). pp. 9053-9058.

Cabodi, S., Tinnirello, A., Bisaro, B., Tornillo, G., Camacho-Leal, M. D., Forni, G., Cojoca, R., Iezzi, M., Amici, A., Montani, M., Eva, A., Di Stefano, P., Muthuswamy, S. K., Tarone, G., Turco, E., Defilippi, P. (October 2010) p130Cas is an essential transducer element in ErbB2 transformation. Faseb J, 24 (10). pp. 3796-3808. ISSN 1530-6860 (Electronic) 0892-6638 (Linking)

Cantallops, I., Cline, H. T. (May 2008) Rapid activity-dependent delivery of the neurotrophic protein CPG15 to the axon surface of neurons in intact Xenopus tadpoles. Dev Neurobiol, 68 (6). pp. 744-759.

Carpino, N., Wisniewski, D., Strife, A., Marshak, D., Kobayashi, R., Stillman, B., Clarkson, B. (January 1997) p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell, 88 (2). pp. 197-204. ISSN 0092-8674 (Print)

Chan, P. M., Nestler, H. P., Miller, W. T. (November 2000) Investigating the substrate specificity of the HER2/Neu tyrosine kinase using peptide libraries. Cancer Letters, 160 (2). pp. 159-169. ISSN 0304-3835

Chardin, P., Camonis, J. H., Gale, N. W., van Aelst, L., Schlessinger, J., Wigler, M. H., Bar-Sagi, D. (May 1993) Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science, 260 (5112). pp. 1338-1343.

Chiu, S. L., Chen, C. M., Cline, H. T. (June 2008) Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo. Neuron, 58 (5). pp. 708-719.

Cline, H. (2008) Experience and brain development. Biological Psychiatry, 63 (7). 222S-222S. ISSN 0006-3223

Clower, C. V., Chatterjee, D., Wang, Z. X., Cantley, L. C., Heiden, M. G. V., Krainer, A. R. (February 2010) The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism. Proceedings of the National Academy of Sciences of the United States of America, 107 (5). pp. 1894-1899. ISSN 0027-8424

Dagnell, M., Frijhoff, J., Pader, I., Augsten, M., Boivin, B., Xu, J., Mandal, P. K., Tonks, N. K., Hellberg, C., Conrad, M., Arnér, E. S. J., Östman, A. (August 2013) Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-ß receptor tyrosine kinase signaling. Proceedings of the National Academy of Sciences of the United States of America, 110 (33). pp. 13398-13403. ISSN 00278424

DeMatteo, R. P., Maki, R. G., Singer, S., Gonen, M., Brennan, M. F., Antonescu, C. R. (March 2007) Results of tyrosine kinase inhibitor therapy followed by surgical resection for metastatic gastrointestinal stromal tumor. Ann Surg, 245 (3). pp. 347-52. ISSN 0003-4932 (Print)0003-4932 (Linking)

Degenhardt, Y., Greshock, J., Laquerre, S., Gilmartin, A. G., Jing, J., Richter, M., Zhang, X., Bleam, M., Halsey, W., Hughes, A., Moy, C., Liu-Sullivan, N., Powers, S., Bachman, K., Jackson, J., Weber, B., Wooster, R. (July 2010) Sensitivity of Cancer Cells to Plk1 Inhibitor GSK461364A Is Associated with Loss of p53 Function and Chromosome Instability. Molecular Cancer Therapeutics, 9 (7). pp. 2079-2089. ISSN 1535-7163

Druker, B. J., Neumann, M., Okuda, K., Franza, B. R., Griffin, J. D. (February 1994) Rel Is Rapidly Tyrosine-Phosphorylated Following Granulocyte-Colony-Stimulating Factor Treatment of Human Neutrophils. Journal of Biological Chemistry, 269 (7). pp. 5387-5390. ISSN 0021-9258

Egeblad, M., Nakasone, E. S., Werb, Z. (June 2010) Tumors as Organs: Complex Tissues that Interface with the Entire Organism. Developmental Cell, 18 (6). pp. 884-901. ISSN 1534-5807

Egeblad, M., Rasch, M. G., Weaver, V. M. (October 2010) Dynamic interplay between the collagen scaffold and tumor evolution. Current Opinion in Cell Biology, 22 (5). pp. 697-706. ISSN 0955-0674

Eifert, C., Wang, X., Kokabee, L., Kourtidis, A., Jain, R., Gerdes, M. J., Conklin, D. S. (October 2013) A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis. Genes Chromosomes and Cancer, 52 (10). pp. 961-975. ISSN 10452257

Fan, G., Nicholas, N. (November 2017) FER mediated HGF-independent regulation of HGFR/MET activates RAC1-PAK1 pathway to potentiate metastasis in ovarian cancer. Small GTPases. ISSN 2154-1248

Fan, G., Zhang, S., Gao, Y., Greer, P. A., Tonks, N. K. (July 2016) HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer. Genes Dev, 30 (13). pp. 1542-57. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Fanta, S., Sonnenberg, M., Skorta, I., Duyster, J., Miething, C., Aulitzky, W. E., van der Kuip, H. (July 2008) Pharmacological inhibition of c-Abl compromises genetic stability and DNA repair in Bcr-Abl-negative cells. Oncogene, 27 (31). pp. 4380-4384. ISSN 0950-9232

Feigin, M. E., Muthuswamy, S. K. (February 2008) ErbB receptors and cell polarity: New pathways and paradigms for understanding cell migration and invasion. Experimental Cell Research, 315 (4). pp. 707-716. ISSN 0014-4827

Fischer, E. H., Charbonneau, H., Cool, D. E., Tonks, N. K. (1992) Tyrosine phosphatases and their possible interplay with tyrosine kinases. Ciba Foundation Symposia, 164. pp. 132-144. ISSN 0300-5208

Fukada, T., Tonks, N. K. (July 2001) The reciprocal role of Egr-1 and Sp family proteins in regulation of the PTP1B promoter in response to the p210 Bcr-Abl oncoprotein-tyrosine kinase. Journal of Biological Chemistry, 276 (27). pp. 25512-25519. ISSN 0021-9258

Fuortes, M., Melchior, M., Han, H., Lyon, G. J., Nathan, C. (August 1999) Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. Journal of Clinical Investigation, 104 (3). pp. 327-335. ISSN 0021-9738

Gounder, M. M., Mahoney, M. R., Van Tine, B. A., Ravi, V., Attia, S., Deshpande, H. A., Gupta, A. A., Milhem, M. M., Conry, R. M., Movva, S., Pishvaian, M. J., Riedel, R. F., Sabagh, T., Tap, W. D., Horvat, N., Basch, E., Schwartz, L. H., Maki, R. G., Agaram, N. P., Lefkowitz, R. A., Mazaheri, Y., Yamashita, R., Wright, J. J., Dueck, A. C., Schwartz, G. K. (December 2018) Sorafenib for Advanced and Refractory Desmoid Tumors. N Engl J Med, 379 (25). pp. 2417-2428. ISSN 0028-4793

Greenberg, M. E., Iafrate, A. J., Skowronski, J. (May 1998) The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. Embo Journal, 17 (10). pp. 2777-89. ISSN 0261-4189

Gurung, Prajwal, Fan, Gaofeng, Lukens, John R., Vogel, Peter, Tonks, Nicholas K., Kanneganti, Thirumala-Devi (April 2017) Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease. Immunity, 46 (4). pp. 635-648. ISSN 1074-7613

Haber, D. A., Bell, D. W., Sordella, R., Kwak, E. L., Godin-Heymann, N., Sharma, S. V., Lynch, T. J., Settleman, J. (2005) Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors. Cold Spring Harbor Symposia on Quantitative Biology, 70. pp. 419-26. ISSN 0091-7451

Hannan, F., Ho, I., Tong, J. J., Zhu, Y., Nurnberg, P., Zhong, Y. (April 2006) Effect of neurofibromatosis type I mutations on a novel pathway for adenylyl cyclase activation requiring neurofibromin and Ras. Hum Mol Genet, 15 (7). pp. 1087-98. ISSN 0964-6906 (Print)

Harrington, R. J., Gutch, M. J., Hengartner, M. O., Tonks, N. K., Chisholm, A. D. (May 2002) The C-elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis. Development, 129 (9). pp. 2141-2153. ISSN 0950-1991

Heisermann, G. J., Gill, G. N. (1991) Identification of phosphorylation sites: use of the epidermal growth factor receptor. Methods in Enzymology, 198. pp. 233-241. ISSN 0076-6879

Hinton, S. D., Myers, M. P., Roggero, V. R., Allison, L. A., Tonks, N. K. (May 2010) The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation. Biochemical Journal, 427. pp. 349-357. ISSN 0264-6021

Huang, L., Muthuswamy, S. K. (February 2010) Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators. Current Opinion in Genetics and Development, 20 (1). pp. 41-50.

Huang, Z. J. (May 2010) Assembly of GABAergic Inhibitory Circuits in Neocortex and Implications in Neurodevelopmental Disorders. Biological Psychiatry, 67 (9). p. 633. ISSN 0006-3223

Janas, J. A., Van Aelst, L. (May 2011) Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Molecular and Cellular Biology, 31 (13). pp. 2552-2565. ISSN 0270-7306

Jung, S. K., Jeong, D. G., Chung, S. J., Kim, J. H., Park, B. C., Tonks, N. K., Ryu, S. E., Kim, S. J. (February 2010) Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor. FASEB J., 24 (2). pp. 560-569. ISSN 0892-6638

Krishnan, N., Krishnan, K., Connors, C. R., Choy, M. S., Page, R., Peti, W., Van Aelst, L., Shea, S. D., Tonks, N. K. (July 2015) PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest, 125 (8). pp. 3163-3177. ISSN 1558-8238 (Electronic)0021-9738 (Linking)

Kumar, S., Pena, L. A., Devellis, J. (January 1993) Cns Glial-Cells Express Neurotrophin Receptors Whose Levels Are Regulated by Ngf. Molecular Brain Research, 17 (1-2). pp. 163-168. ISSN 0169-328X

La Montagne, K. R., Flint, A. J., Franza, B. R., Pendergast, A. M., Tonks, N. K. (May 1998) Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo. Molecular and Cellular Biology, 18 (5). pp. 2965-2975. ISSN 0270-7306

Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., Parsons, R. (March 1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 275 (5308). pp. 1943-7. ISSN 0036-8075 (Print)

Li, N., Batzer, A., Daly, R., Yajnik, V., Skolnik, E., Chardin, P., Bar-Sagi, D., Margolis, B., Schlessinger, J. (May 1993) Guanine-Nucleotide-Releasing Factor Hsos1 Binds to Grb2 and Links Receptor Tyrosine Kinases to Ras Signaling. Nature, 363 (6424). pp. 85-88. ISSN 0028-0836

Lowenstein, E. J., Daly, R. J., Batzer, A. G., Li, W., Margolis, B., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar-Sagi, D., Schlessinger, J. (August 1992) The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell, 70 (3). pp. 431-42. ISSN 0092-8674 (Print)0092-8674 (Linking)

Lucs, A. V., Muller, W. J., Muthuswamy, S. K. (January 2010) Shc is required for ErbB2-induced inhibition of apoptosis but is dispensable for cell proliferation and disruption of cell polarity. Oncogene, 29 (2). pp. 174-187. ISSN 0950-9232

Lundgren, K., Beach, D. (1991) Mik1 and Wee1 Mitotic Inhibitors Cooperate in Cdc2 Tyrosine Phosphorylation. Journal of Cell Biology, 115 (3 PART). 423A.

Lundgren, K., Walworth, N., Booher, R., Dembski, M., Kirschner, M., Beach, D. (March 1991) mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell, 64 (6). pp. 1111-22. ISSN 0092-8674 (Print)0092-8674 (Linking)

Lynch, T. J., Bell, D. W., Sordella, R., Gurubhagavatula, S., Okimoto, R. A., Brannigan, B. W., Harris, P. L., Haserlat, S. M., Supko, J. G., Haluska, F. G., Louis, D. N., Christiani, D. C., Settleman, J., Haber, D. A. (May 2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. The New England Journal of Medicine, 350 (21). pp. 2129-39. ISSN 1533-4406 (Electronic)

Morla, A. O., Draetta, G., Beach, D., Wang, J. Y. J. (July 1989) Reversible Tyrosine Phosphorylation of Cdc2 - Dephosphorylation Accompanies Activation During Entry into Mitosis. Cell, 58 (1). pp. 193-203. ISSN 0092-8674

Moskal, D., Tonks, N. K., Lucito, R. (August 2015) Alteration of the protein tyrosine phosphatome in cancer. Cancer Research, 75 (Supple). Abstract 1933. ISSN 0008-5472

Myers, M. P., Andersen, J. N., Cheng, A., Tremblay, M. L., Horvath, C. M., Parisien, J. P., Salmeen, A., Barford, D., Tonks, N. K. (December 2001) TYK2 and JAR2 are substrates of protein-tyrosine phosphatase 1B. Journal of Biological Chemistry, 276 (51). pp. 47771-47774. ISSN 0021-9258

Myers, M. P., Pass, I., Batty, I. H., Van der Kaay, J., Stolarov, J. P., Hemmings, B. A., Wigler, M. H., Downes, C. P., Tonks, N. K. (November 1998) The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A, 95 (23). pp. 13513-8. ISSN 0027-8424 (Print)

Neumann, M., Tsapos, K., Scheppler, J. A., Ross, J., Franza, B. R. (November 1992) Identification of Complex-Formation between 2 Intracellular Tyrosine Kinase Substrates - Human C-Rel and the P105 Precursor of P50 Nf-Kappa-B. Oncogene, 7 (11). pp. 2095-2104. ISSN 0950-9232

Niki, M., Di Cristofano, A., Zhao, M., Honda, H., Hirai, H., Van Aelst, L., Cordon-Cardo, C., Pandolfi, P. P. (December 2004) Role of Dok-1 and Dok-2 in leukemia suppression. J Exp Med, 200 (12). pp. 1689-95.

Niki, M., Di Cristofano, A., Zhao, M. M., Honda, H., Hirai, H., Van Aelst, L., Cordon-Cardo, C., Pandolfi, P. P. (December 2004) Role of Dok-1 and Dok-2 in leukemia suppression. Journal of Experimental Medicine, 200 (12). pp. 1689-1695. ISSN 0022-1007

Oliver, T. G., Mercer, K. L., Sayles, L. C., Burke, J. R., Mendus, D., Lovejoy, K. S., Cheng, M. H., Subramanian, A., Mu, D., Powers, S., Crowley, D., Bronson, R. T., Whittaker, C. A., Bhutkar, A., Lippard, S. J., Golub, T., Thomale, J., Jacks, T., Sweet-Cordero, E. A. (April 2010) Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes & Development, 24 (8). pp. 837-852. ISSN 0890-9369

Palmerini, E., Staals, E. L., Maki, R. G., Pengo, S., Cioffi, A., Gambarotti, M., Picci, P., Daolio, P. A., Parafioriti, A., Morris, C., Antonescu, C. R., Gronchi, A., Casali, P. G., Donati, D. M., Ferrari, S., Stacchiotti, S. (January 2015) Tenosynovial giant cell tumour/pigmented villonodular synovitis: outcome of 294 patients before the era of kinase inhibitors. Eur J Cancer, 51 (2). pp. 210-7. ISSN 1879-0852 (Electronic)0959-8049 (Linking)

Paoluzzi, L., Maki, R. G. (October 2018) Diagnosis, Prognosis, and Treatment of Alveolar Soft-Part Sarcoma: A Review. JAMA Oncol, 5 (2). pp. 254-260. ISSN 2374-2437

Pineau, P., Volinia, S., McJunkin, K., Marchio, A., Battiston, C., Terris, B., Mazzaferro, V., Lowe, S. W., Croce, C. M., Dejean, A. (January 2010) miR-221 overexpression contributes to liver tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America, 107 (1). pp. 264-269. ISSN 0027-8424

Reyes, G., Niederst, M., Cohen-Katsenelson, K., Stender, J. D., Kunkel, M. T., Chen, M., Brognard, J., Sierecki, E., Gao, T., Nowak, D. G., Trotman, L. C., Glass, C. K., Newton, A. C. (September 2014) Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output. Proc Natl Acad Sci U S A, 111 (38). E3957-E3965. ISSN 0027-8424

Sadowski, Henry B., Gilman, Michael Z. (March 1993) Cell-free activation of a DNA-binding protein by epidermal growth factor. Nature, 362 (6415). pp. 79-83.

Schumann, G., Rujescu, D., Kissling, C., Soyka, M., Dahmen, N., Preuss, U. W., Wieman, S., Depner, M., Wellek, S., Lascorz, J., Bondy, B., Giegling, I., Anghelescu, I., Cowen, M. S., Poustka, A., Spanagel, R., Mann, K., Henn, F. A., Szegedi, A. (December 2003) Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts. Biol Psychiatry, 54 (12). pp. 1422-6. ISSN 0006-3223 (Print)0006-3223 (Linking)

Schwertassek, U., Buckley, D. A., Xu, C. F., Lindsay, A. J., McCaffrey, M. W., Neubert, T. A., Tonks, N. K. (June 2010) Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis. Febs Journal, 277 (11). pp. 2463-2473. ISSN 1742-464X

Sharma, S., Birchmeier, C., Nikawa, J., O'Neill, K., Rodgers, L., Wigler, M. H. (1989) Characterization of the ros1-gene products expressed in human glioblastoma cell lines. Oncogene Res, 5 (2). pp. 91-100. ISSN 0890-6467

Shual, K., Ziemiecki, A., Wilks, A. F., Harpur, A. G., Sadowski, H. B., Gilman, M. Z., Darnell, J. E. (December 1993) Polypeptide Signaling to the Nucleus through Tyrosine Phosphorylation of Jak and Stat Proteins. Nature, 366 (6455). pp. 580-583. ISSN 0028-0836

Smolen, G. A., Sordella, R., Muir, B., Mohapatra, G., Barmettler, A., Archibald, H., Kim, W. J., Okimoto, R. A., Bell, D. W., Sgroi, D. C., Christensen, J. G., Settleman, J., Haber, D. A. (February 2006) Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proceedings of the National Academy of Sciences of the United States of America, 103 (7). pp. 2316-21. ISSN 0027-8424

Sordella, R., Bell, D. W., Haber, D. A., Settleman, J. (August 2004) Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science, 305 (5687). pp. 1163-7. ISSN 1095-9203 (Electronic)

Stegh, A. H., Kim, H., Bachoo, R. M., Forloney, K. L., Zhang, J., Schulze, H., Park, K., Hannon, G. J., Yuan, J. Y., Louis, D. N., DePinho, R. A., Chin, L. (January 2007) Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma. Genes Dev, 21 (1). pp. 98-111. ISSN 0890-9369

Sun, H., Tonks, N. K. (November 1994) The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends in Biochemical Sciences, 19 (11). pp. 480-485. ISSN 0968-0004

Szele, F. G., Walker, A. S., Goings, G. E., Kim, Y., Miller, R. J., Chenn, A. (2010) Nestin reporter transgene labels multiple central nervous system precursor cells. Neural Plasticity, 2010. ISSN 07928483 (ISSN)

Tonks, N. K. (November 2006) Protein tyrosine phosphatases: from genes, to function, to disease. Nat Rev Mol Cell Biol, 7 (11). pp. 833-46. ISSN 1471-0072 (Print)

Tsigankov, D., Koulakov, A. A. (December 2010) Sperry versus Hebb: topographic mapping in Isl2/EphA3 mutant mice. BMC Neurosci, 11. p. 155. ISSN 1471-2202 (Electronic) 1471-2202 (Linking)

Turner, B. C., Tonks, N. K., Rapp, U. R., Reed, J. C. (June 1993) Interleukin-2 Regulates Raf-1 Kinase-Activity through a Tyrosine Phosphorylation-Dependent Mechanism in a T-Cell Line. Proceedings of the National Academy of Sciences of the United States of America, 90 (12). pp. 5544-5548. ISSN 0027-8424

Van Aelst, L., Barr, M., Marcus, S., Polverino, A., Wigler, M. H. (July 1993) Complex formation between RAS and RAF and other protein kinases. Proc Natl Acad Sci U S A, 90 (13). pp. 6213-7. ISSN 0027-8424 (Print)

Venkitaramani, D. V., Chin, J., Netzer, W. J., Gouras, G. K., Lesne, S., Malinow, R., Lombroso, P. J. (October 2007) beta-amyloid modulation of synaptic transmission and plasticity. Journal of Neuroscience, 27 (44). pp. 11832-11837. ISSN 0270-6474

Vignais, M. L., Sadowski, H. B., Watling, D., Rogers, N. C., Gilman, M. (April 1996) Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. Molecular and Cellular Biology, 16 (4). pp. 1759-69. ISSN 0270-7306

Wang, S. E., Narasanna, A., Perez-Torres, M., Xiang, B., Wu, F. Y., Yang, S., Carpenter, G., Gazdar, A. F., Muthuswamy, S. K., Arteaga, C. L. (2006) HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell, 10 (1). pp. 25-38. ISSN 15356108

Wang, S. M., Zhang, M. Q. (February 2010) Transcriptome Study for Early Hematopoiesis-Achievement, Challenge and New Opportunity. Journal of Cellular Physiology, 223 (3). pp. 549-552. ISSN 0021-9541

Wu, G. M., Feng, X., Stein, L. D. (May 2010) A human functional protein interaction network and its application to cancer data analysis. Genome Biology, 11 (5). ISSN 1474-760X

Xu, M. Z., Chan, S. W., Liu, A. M., Wong, K. F., Fan, S. T., Chen, J., Poon, R. T., Zender, L., Lowe, S. W., Hong, W., Luk, J. M. (March 2011) AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma. Oncogene, 30 (10). pp. 1229-1240.

Yao, Z., Fenoglio, S., Gao, D. C., Camiolo, M., Stiles, B., Lindsted, T., Schlederer, M., Johns, C., Altorki, N., Mittal, V., Kenner, L., Sordella, R. (August 2010) TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proceedings of the National Academy of Sciences of the United States of America, 107 (35). pp. 15535-40. ISSN 0027-8424

Zhan, L., Xiang, B., Muthuswamy, S. K. (May 2006) Controlled activation of ErbB1/ErbB2 heterodimers promote invasion of three-dimensional organized epithelia in an ErbB1-dependent manner: implications for progression of ErbB2-overexpressing tumors. Cancer Res, 66 (10). pp. 5201-8. ISSN 0008-5472 (Print)

van der Horst, E. H., Degenhardt, Y. Y., Strelow, A., Slavin, A., Chinn, L., Orf, J., Rong, M., Li, S., See, L. H., Nguyen, K. Q., Hoey, T., Wesche, H., Powers, S. (November 2005) Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1. Proceedings of the National Academy of Sciences of the United States of America, 102 (44). pp. 15901-6. ISSN 0027-8424

Conference or Workshop Item

Aiken, C., Luban, J. (May 2010) RETROVIRUSES. In: 2010 meeting of RETROVIRUSES, May 24–May 29, 2010, Cold Spring Harbor Laboratory.

Aloy, P., Gavin, A. C., Ideker, T., Walhout, M. (August 2010) SYSTEMS BIOLOGY: NETWORKS. In: Joint Cold Spring Harbor Laboratory/Wellcome Trust Conference on SYSTEMS BIOLOGY: NETWORKS, August 11–August 15, 2010, Wellcome Trust Conference Center, Hixton UK.

Anderson, K., Koseki, H., Skarnes, W., Shen, M. (October 2010) MOUSE DEVELOPMENT,GENETICS & GENOMICS. In: 2010 meeting on MOUSE DEVELOPMENT,GENETICS & GENOMICS, October 26–October 30, 2010, Cold Spring Harbor Laboratory.

Bainton, R., Barres, B., Daneman, R. (December 2010) BLOOD-BRAIN BARRIER. In: 2010 Meeting of December 8–December 11, 2010, December 8–December 11, 2010, Cold Spring Harbor Laboratory.

Baker, S., Cantley, L., Paolo Pandolfi, P., Parsons, R. (March 2010) PTEN PATHWAYS & TARGETS. In: 2010 meeting of PTEN PATHWAYS & TARGETS, March 16–March 20, 2010, Cold Spring Harbor Laboratory.

Bar-Sagi, D., Lees, J., Sherr, C., Weiss, W. (August 2010) MECHANISMS & MODELS OF CANCER. In: 2010 meeting of MECHANISMS & MODELS OF CANCER, August 17–August 21, 2010, Cold Spring Harbor Laboratory.

Bargmann, C., Callaway, E., Chklovskii, D. (March 2010) NEURONAL CIRCUITS. In: 2010 Meeting of Neuronal Circuits, March 10–March 13, 2010, Cold Spring Harbor Laboratory.

Bernstein, B., Bulyk, M., Bussemaker, H., Walhout, M. (March 2010) SYSTEMS BIOLOGY: GLOBAL REGULATION OF GENE EXPRESSION. In: 2010 meeting on SYSTEMS BIOLOGY: GLOBAL REGULATION OF GENE EXPRESSION, March 23–March 27, 2010.

Birol, I., Champ, M., Cant, J. (September 2010) GENOME INFORMATICS. In: Joint Cold Spring Harbor Laboratory/Wellcome Trust Conference on GENOME INFORMATICS, September 15–September 19, 2010, Wellcome Conference Center.

Bray, D., Le Novere, N., Lowe, L. (February 2010) COMPUTATIONAL CELL BIOLOGY. In: Joint Cold Spring Harbor Laboratory/Wellcome Trust Conference on Computational Cell Biology, February 10–February 13, 2010, Wellcome Trust Hixton Conference Center UK.

Cantrell, D., Gsosh, S., Littman, D., Schlissel, M. (April 2010) GENE EXPRESSION & SIGNALING IN THE IMMUNE SYSTEM. In: 2010 meeting of GENE EXPRESSION & SIGNALING IN THE IMMUNE SYSTEM, April 21–April 25, 2010, Cold Spring Harbor Laboratory.

Church, G., Flicek, P., Ribbs, R., Mardis, E. (September 2010) PERSONAL GENOMES. In: 2010 meeting on PERSONAL GENOMES, September 10–September 12, 2010.

Davis, G., Kolodkin, A., Mason, C. (September 2010) AXON GUIDANCE, SYNAPTIC PLASTICITY & REGENERATION. In: 2010 Meeting of AXON GUIDANCE, SYNAPTIC PLASTICITY & REGENERATION, September 21–September 25, 2010, Cold Spring Harbor Laboratory.

Dever, T., Fox, P., Hinnebusch, A., Izaurralde, E. (September 2010) TRANSLATIONAL CONTROL. In: 2010 meeting on TRANSLATIONAL CONTROL, September 13–September 17, 2010, Cold Spring Harbor Laborator.

Eppig, J., Fuller, M., Newmark, P. (October 2010) GERM CELLS. In: 2010 Meeting of Germ Cells, October 5–October 9, 2010.

Epstein, J., Hogan, B., Oliver, G. (April 2010) VERTEBRATE ORGANOGENESIS. In: 2010 meeting on VERTEBRATE ORGANOGENESIS, April 27–May 1, 2010, Cold Spring Harbor Laboratory.

Evans, R., Olefsky, J., Yamamoto, K. (August 2010) NUCLEAR RECEPTORS & DISEASE. In: 2010 meeting on NUCLEAR RECEPTORS & DISEASE, August 31–September 4, 2010.

Gandy, S., Man-Yee Lee, V., Rothstein, J. (December 2010) NEURODEGENERATIVE DISEASES: BIOLOGY & THERAPEUTICS. In: 2010 meeting of Neurodegenerative diseases, December 1–December 4, 2010, Cold Spring Larbor Laboratory.

Hu, J., Levin, P., Winkler, M. (August 2010) MOLECULAR GENETICS OF BACTERIA & PHAGES. In: 2010 meeting of MOLECULAR GENETICS OF BACTERIA & PHAGES, August 24–August 28, 2010, Cold Spring Harbor Laboratory.

Stevens, B., Talbot, W. (July 2010) GLIA IN HEALTH & DISEASE. In: Abstracts of 2010 meeting of GLIA IN HEALTH & DISEASE, July 22–July 26, 2010, Cold Spring Harbor Laboratory.

Ulrich Hartl, F., Ron, D., Weissman, J. (May 2010) MOLECULAR CHAPERONES & STRESS RESPONSES. In: 2010 meeting of MOLECULAR CHAPERONES & STRESS RESPONSES, May 4–May 8, 2010, Cold Spring Larbor Laboratory.

Thesis

Pineda, Maria L (September 2012) Substrate specificity of receptor tyrosine kinases is critical for selective signaling. PhD thesis, Cold Spring Harbor Laboratory.