Items where Subject is "shRNA"

A

Albers, C., Illert, A. L., Miething, C., Leischner, H., Thiede, M., Peschel, C., Duyster, J. (August 2011) An RNAi-based system for loss-of-function analysis identifies Raf1 as a crucial mediator of BCR-ABL - Driven leukemogenesis. Blood, 118 (8). pp. 2200-2210. ISSN 00064971 (ISSN)

B

Bric, A., Miething, C., Bialucha, C. U., Scuoppo, C., Zender, L., Krasnitz, A., Xuan, Z., Zuber, J., Wigler, M. H., Hicks, J. B., McCombie, W. R., Hemann, M. T., Hannon, G. J., Powers, S., Lowe, S. W. (October 2009) Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model. Cancer Cell, 16 (4). pp. 324-35. ISSN 1535-6108

C

Chang, K., Elledge, S. J., Hannon, G. J. (September 2006) Lessons from Nature: microRNA-based shRNA libraries. Nat Methods, 3 (9). pp. 707-14. ISSN 1548-7091 (Print)

Chen, C. M., Chiu, S. L., Shen, W., Cline, H. T. (2009) Co-expression of Argonaute2 Enhances Short Hairpin RNA-induced RNA Interference in Xenopus CNS Neurons In Vivo. Frontiers in Neuroscience, 3. p. 63.

Chitwood, D. H., Timmermans, M. C. P. (September 2010) Small RNAs are on the move. Nature, 467 (7314). pp. 415-419. ISSN 0028-0836

Cifuentes, D., Xue, H. L., Taylor, D. W., Patnode, H., Mishima, Y., Cheloufi, S., Ma, E. B., Mane, S., Hannon, G. J., Lawson, N. D., Wolfe, S. A., Giraldez, A. J. (June 2010) A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity. Science, 328 (5986). pp. 1694-1698. ISSN 0036-8075

D

Dahlman, K. B., Parker, J. S., Shamu, T., Hieronymus, H., Chapinski, C., Carver, B., Chang, K., Hannon, G. J., Sawyers, C. L. (2012) Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening. PLoS One, 7 (4). ISSN 19326203 (ISSN)

Dickins, R. A., Hemann, M. T., Zilfou, J. T., Simpson, D. R., Ibarra, I., Hannon, G. J., Lowe, S. W. (November 2005) Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat Genet, 37 (11). pp. 1289-95. ISSN 1061-4036 (Print)

Dow, L. E., Premsrirut, P. K., Zuber, J., Fellmann, C., McJunkin, K., Miething, C., Park, Y., Dickins, R. A., Hannon, G. J., Lowe, S. W. (2012) A pipeline for the generation of shRNA transgenic mice. Nature Protocols, 7 (2). pp. 374-393. ISSN 17542189 (ISSN)

F

Fellmann, C., Zuber, J., McJunkin, K., Chang, K. , Malone, C. D., Dickins, R. A., Xu, Q., Hengartner, M. O., Elledge, S. J., Hannon, G. J., Lowe, S. W. (March 2011) Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay. Molecular Cell, 41 (6). pp. 733-746. ISSN 1097-2765

G

Ghafoori, A., Lee, C., Perez, B., Johnston, S., Rodrigues, R., Badea, C., Kim, Y., Lowe, S. W., Kirsch, D. G. (2009) In Vivo shRNA to Study the Molecular Mechanisms of Radiation Response of Primary Cancers in Mice. International Journal of Radiation Oncology Biology Physics, 75 (3). S171-S172. ISSN 0360-3016

Golding, M. C., Long, C. R., Carmell, M. A., Hannon, G. J., Westhusin, M. E. (April 2006) Suppression of prion protein in livestock by RNA interference. Proc Natl Acad Sci U S A, 103 (14). pp. 5285-90. ISSN 0027-8424 (Print)

Gupta, S., Schoer, R. A., Egan, J. E., Hannon, G. J., Mittal, V. (February 2004) Inducible, reversible, and stable RNA interference in mammalian cells. Proc Natl Acad Sci U S A, 101 (7). pp. 1927-32. ISSN 0027-8424 (Print)

H

Hemann, M. T., Zilfou, J. T., Zhao, Z., Burgess, D. J., Hannon, G. J., Lowe, S. W. (June 2004) Suppression of tumorigenesis by the p53 target PUMA. Proc Natl Acad Sci U S A, 101 (25). pp. 9333-8. ISSN 0027-8424 (Print)

K

Knott, S. R., Maceli, A. R., Erard, N., Chang, K., Marran, K., Zhou, X., Gordon, A., El Demerdash, O., Wagenblast, E., Kim, S., Fellmann, C., Hannon, G. J. (December 2014) A Computational Algorithm to Predict shRNA Potency. Mol Cell, 56 (6). pp. 796-807. ISSN 1097-2765

L

Liu-Sullivan, N., Zhang, J., Bakleh, A., Marchica, J., Li, J., Siolas, D., Laquerre, S., Degenhardt, Y. Y., Wooster, R., Chang, K., Hannon, G. J., Powers, S. (December 2011) Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1). Oncotarget, 2 (12). pp. 1254-64. ISSN 1949-2553 (Electronic) 1949-2553 (Linking)

M

Maroney, P. A., Hannon, G. J., Denker, J. A., Nilsen, T. W. (1990) The nematode spliced leader RNA participates in trans-splicing as an Sm snRNP. Embo Journal, 9 (11). pp. 3667-3673. ISSN 0261-4189

McCaffrey, A. P., Meuse, L., Pham, T. T. T., Conklin, D. S., Hannon, G. J., Kay, M. A. (July 2002) Gene expression - RNA interference in adult mice. Nature, 418 (6893). pp. 38-39. ISSN 0028-0836

N

Ni, J. Q., Zhou, R., Czech, B., Liu, L. P., Holderbaum, L., Yang-Zhou, D., Shim, H. S., Tao, R., Handler, D., Karpowicz, P., Binari, R., Booker, M., Brennecke, J., Perkins, L. A., Hannon, G. J., Perrimon, N. (2011) A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nature Methods, 8 (5). pp. 405-407. ISSN 15487091 (ISSN)

O

Olson, A., Sheth, N., Lee, J. S., Hannon, G. J., Sachidanandam, R. (January 2006) RNAi Codex: a portal/database for short-hairpin RNA (shRNA) gene-silencing constructs. Nucleic Acids Res, 34 (Databa). D153-7. ISSN 1362-4962 (Electronic)

P

Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J., Conklin, D. S. (2002) Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes and Development, 16 (8). pp. 948-958. ISSN 08909369 (ISSN)

Paddison, P. J., Cleary, M., Silva, J. M., Chang, K., Sheth, N., Sachidanandam, R., Hannon, G. J. (November 2004) Cloning of short hairpin RNAs for gene knockdown in mammalian cells. Nat Methods, 1 (2). pp. 163-7. ISSN 1548-7091 (Print)

Paddison, P. J., Hannon, G. J. (2003) siRNAs and shRNAs: Skeleton keys to the human genome. Current Opinion in Molecular Therapeutics, 5 (3). pp. 217-224. ISSN 14648431 (ISSN)

Paddison, P. J., Silva, J. M., Conklin, D. S., Schlabach, M., Li, M., Aruleba, S., Balija, V., O'Shaughnessy, A., Gnoj, L., Scobie, K., Chang, K., Westbrook, T., Cleary, M., Sachidanandam, R., McCombie, W. R., Elledge, S. J., Hannon, G. J. (March 2004) A resource for large-scale RNA-interference-based screens in mammals. Nature, 428 (6981). pp. 427-31. ISSN 1476-4687 (Electronic)

Premsrirut, P. K., Dow, L. E., Kim, S. Y., Camiolo, M., Malone, C. D., Miething, C., Scuoppo, C. , Zuber, J., Dickins, R. A., Kogan, Scott C, Shroyer, Kenneth R, Sordella, R., Hannon, G. J., Lowe, S. W. (March 2011) A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference. Cell, 145 (1). pp. 145-158. ISSN 0092-8674

R

Reed, M. F., Zagorski, W. A., Howington, J. A., Zilfou, J. T., Knudsen, E. S. (2006) Inhibition of Retinoblastoma Tumor Suppressor Activity by RNA Interference in Lung Cancer Lines. Annals of Thoracic Surgery, 82 (1). pp. 249-253. ISSN 00034975

S

Schlabach, M. R., Luo, J., Solimini, N. L., Hu, G., Xu, Q. K., Li, M. Z., Zhao, Z. M., Smogorzewska, A., Sowa, M. E., Ang, X. L. L., Westbrook, T. F., Liang, A. C., Chang, K., Hackett, J. A., Harper, J. W., Hannon, G. J., Elledge, S. J. (February 2008) Cancer proliferation gene discovery through functional Genomics. Science, 319 (5863). pp. 620-624. ISSN 0036-8075

Silva, J., Chang, K., Hannon, G. J., Rivas, F. V. (November 2004) RNA-interference-based functional genomics in mammalian cells: reverse genetics coming of age. Oncogene, 23 (51). pp. 8401-9. ISSN 0950-9232 (Print)

Siolas, D., Lerner, C., Burchard, J., Ge, W., Linsley, P. S., Paddison, P. J., Hannon, G. J., Cleary, M. A. (February 2005) Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol, 23 (2). pp. 227-31. ISSN 1087-0156 (Print)

Stegmeier, F., Hu, G., Rickles, R. J., Hannon, G. J., Elledge, S. J. (September 2005) A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 102 (37). pp. 13212-13217. ISSN 0027-8424

T

Tan, X., Lu, Z. J., Gao, G., Xu, Q., Hu, L., Fellmann, C., Li, M. Z., Qu, H., Lowe, S. W., Hannon, G. J., Elledge, S. J. (2012) Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy. Proceedings of the National Academy of Sciences of the United States of America, 109 (3). pp. 869-874. ISSN 00278424 (ISSN)

Tessanne, K., Golding, M. C., Long, C. R., Peoples, M. D., Hannon, G., Westhusin, M. E. (March 2012) Production of transgenic calves expressing an shRNA targeting myostatin. Molecular Reproduction and Development, 79 (3). pp. 176-185. ISSN 1040452X (ISSN)

Tessanne, K., Stroud, T., Long, C., Hannon, G. J., Sadeghieh, S., Hwang, E., Chen, S., Polejaeva, I., Westhusin, M. (2009) Development of Transgenic Livestock with Reduced Myostatin Expression Using Rna Interference. Reproduction Fertility and Development, 21 (1). p. 251. ISSN 1031-3613

Z

Zender, L., Xue, W., Zuber, J., Semighini, C. P., Krasnitz, A., Ma, B., Zender, P., Kubicka, S., Luk, J. M., Schirmacher, P., McCombie, W. R., Wigler, M. H., Hicks, J. B., Hannon, G. J., Powers, S., Lowe, S. W. (November 2008) An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer. Cell, 135 (5). pp. 852-864. ISSN 0092-8674

Zuber, J., McJunkin, K., Fellmann, C., Dow, L. E., Taylor, M. J., Hannon, G. J., Lowe, S. W. (January 2011) Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNA. Nature Biotechnology, 29 (1). pp. 79-85.

Zuber, J., Shi, J., Wang, E., Rappaport, A. R., Herrmann, H., Sison, E. A., Magoon, D., Qi, J., Blatt, K., Wunderlich, M., Taylor, M. J., Johns, C., Chicas, A., Mulloy, J. C., Kogan, S. C., Brown, P., Valent, P., Bradner, J. E., Lowe, S. W., Vakoc, C. R. (August 2011) RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature, 478 (7370). pp. 524-528. ISSN 0028-0836