Items where Subject is "gene silencing"

A

Andl, T., Murchison, E. P., Liu, Fei, Zhang, Yi, Yunta-Gonzalez, M., Tobias, J. W., Andl, C. D., Seykora, J. T., Hannon, G. J., Millar, S. E. (May 2006) The miRNA-Processing Enzyme Dicer Is Essential for the Morphogenesis and Maintenance of Hair Follicles. Current Biology, 16 (10). pp. 1041-1049. ISSN 09609822

Aravin, A. A., Gaidatzis, D., Pfeffer, S., Lagos-Quintana, M., Landgraf, P., Iovino, N., Morris, P., Brownstein, M. J., Kuramochi-Miyagawa, S., Nakano, T., Chien, M. C., Russo, J. J., Ju, J. Y., Sheridan, R., Sander, C., Zavolan, M. , Tuschl, T. (July 2006) A novel class of small RNAs bind to MILI protein in mouse testes. Nature, 442 (7099). pp. 203-7. ISSN 1476-4687 (Electronic)

B

Bastow, R., Mylne, J. S., Lister, C., Lippman, Z., Martienssen, R. A., Dean, C. (January 2004) Vernalization requires epigenetic silencing of FLC by histone methylation. Nature, 427 (6970). pp. 164-7. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Bell, S. P., Kobayashi, R., Stillman, B. (February 1994) Transcriptional Silencing, DNA-Replication, and the Yeast Origin Recognition Complex. Journal of Cellular Biochemistry, 56 (S18C). p. 82. ISSN 0730-2312

Bhattacharjee, S., Roche, B., Martienssen, R. A. (June 2019) RNA-induced initiation of transcriptional silencing (RITS) complex structure and function. RNA Biol, 16 (9). pp. 1133-1146. ISSN 1547-6286

C

Canto-Pastor, A., Molla-Morales, A., Ernst, E., Dahl, W., Zhai, J., Yan, Y., Meyers, B. C., Shanklin, J., Martienssen, R. (January 2015) Efficient transformation and artificial miRNA gene silencing in Lemna minor. Plant Biol (Stuttg), 17 (s1). pp. 59-65. ISSN 1435-8603

Carmell, M. A., Hannon, G. J. (2004) Achieving stable, heritable gene silencing in the mouse. In: RNA interference (RNAI) : the nuts & bolts of sirna technology. The Nuts & Bolts series . DNA Press, Eagleville, PA , pp. 217-234. ISBN 0966402782

Chang, K., Marran, K., Valentine, A., Hannon, G. J. (2012) RNAi in cultured mammalian cells using synthetic siRNAs. Cold Spring Harbor Protocols, 7 (9). pp. 957-961. ISSN 19403402

Chicas, A., Kapoor, A., Wang, X. W., Aksoy, O., Evertts, A. G., Zhang, M. Q., Garcia, B. A., Bernstein, E., Lowe, S. W. (June 2012) H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proceedings of the National Academy of Sciences of the United States of America, 109 (23). pp. 8971-8976. ISSN 0027-8424

Conklin, D. S. (October 2003) RNA-interference-based silencing of mammalian gene expression. Chembiochem, 4 (10). pp. 1033-1039. ISSN 1439-4227

Connelly, J. J., Yuan, P., Hsu, H. C., Li, Z., Xu, R. M., Sternglanz, R. (April 2006) Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain. Mol Cell Biol, 26 (8). pp. 3256-65. ISSN 0270-7306 (Print)

D

Diffley, J. F. X., Stillman, B. (1990) Ars Binding Factors in DNA Replication and Transcriptional Silencing. Yeast, 6 (SPEC. ). S12.

Diffley, J. F. X., Stillman, B. (November 1989) Transcriptional Silencing and Lamins. Nature, 342 (6245). p. 24. ISSN 0028-0836

Ding, J. X., Feng, Y. J., Yao, L. Q., Yu, M., Jin, H. Y., Yin, L. H. (2006) The reinforcement of invasion in epithelial ovarian cancer cells by 17?-Estradiol is associated with up-regulation of Snail. Gynecologic Oncology, 103 (2). pp. 623-630. ISSN 00908258

E

Elkayam, Elad, Faehnle, Christopher R., Morales, Marjorie, Sun, Jingchuan, Li, Huilin, Joshua-Tor, Leemor (August 2017) Multivalent Recruitment of Human Argonaute by GW182. Molecular Cell, 67 (4). pp. 646-658. ISSN 1097-2765 (Public Dataset)

Esposito, D., Fassina, G., Szabo, P., Deangelis, P., Rodgers, L., Weksler, M., Siniscalco, M. (February 1989) Chromosomes of Older Humans Are More Prone to Aminopterine-Induced Breakage. Proceedings of the National Academy of Sciences of the United States of America, 86 (4). pp. 1302-1306. ISSN 0027-8424

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Fan, G., Zhang, S., Gao, Y., Greer, P. A., Tonks, N. K. (July 2016) HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer. Genes Dev, 30 (13). pp. 1542-57. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Fang, F., Fan, S., Zhang, X., Zhang, M. Q. (2006) Predicting methylation status of CpG islands in the human brain. Bioinformatics, 22 (18). pp. 2204-2209. ISSN 13674803

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Golding, M. C., Long, C. R., Carmell, M. A., Hannon, G. J., Westhusin, M. E. (April 2006) Suppression of prion protein in livestock by RNA interference. Proc Natl Acad Sci U S A, 103 (14). pp. 5285-90. ISSN 0027-8424 (Print)

Gutbrod, M. J., Martienssen, R. A. (May 2020) Conserved chromosomal functions of RNA interference. Nat Rev Genet, 21 (5). pp. 311-331. ISSN 1471-0056

H

Hall, I. M. (November 2003) A Role for RNA Interference in Heterochromatic Silencing and Chromosome Dynamics. PhD thesis, Cold Spring Harbor Laboratory.

Hall, I. M., Grewal, S. I. S. (2003) Structure and function of heterochromatin: implications for epigenetic gene silencing and genome organization. In: RNAi : a guide to gene silencing. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y. , pp. 205-232. ISBN 978-087969641-2

Hammond, S. M., Caudy, A. A., Hannon, G. J. (2001) Post-transcriptional gene silencing by double-stranded RNA. Nature Reviews Genetics, 2 (2). pp. 110-119. ISSN 14710056 (ISSN)

Hemann, M. T., Fridman, J. S., Zilfou, J. T., Hernando, E., Paddison, P. J., Cordon-Cardo, C., Hannon, G. J., Lowe, S. W. (March 2003) An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nature Genetics, 33 (3). pp. 396-400. ISSN 1061-4036

Hsu, H. C., Stillman, B., Xu, R. M. (June 2005) Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing. Proc Natl Acad Sci U S A, 102 (24). pp. 8519-24. ISSN 0027-8424 (Print)

Hu, Y., Wu, Q., Peng, Z., Sprague, S. A., Wang, W., Park, J., Akhunov, E., Jagadish, K. S. V., Nakata, P. A., Cheng, N., Hirschi, K. D., White, F. F., Park, S. (November 2017) Silencing of OsGRXS17 in rice improves drought stress tolerance by modulating ROS accumulation and stomatal closure. Sci Rep, 7 (1). p. 15950. ISSN 2045-2322

Hu, Y, Tareen, A., Sheu, Y. J., Ireland, W. T., Speck, C., Li, H., Joshua-Tor, L., Kinney, J. B., Stillman, B. (October 2020) Evolution of DNA replication origin specification and gene silencing mechanisms. Nature Communications, 11 (1). p. 5175. ISSN 2041-1723

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Ipsaro, Jonathan J, O'Brien, Paul A, Bhattacharya, Shibani, Palmer, Arthur G, Joshua-Tor, Leemor (March 2021) Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. Cell Reports, 34 (13). p. 108914. ISSN 2211-1247

Ipsaro, Jonathan J, O’Brien, Paul A, Bhattacharya, Shibani, Palmer, Arthur G, Joshua-Tor, Leemor (August 2020) Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. BioRxiv. (Unpublished)

J

Joshua-Tor, L. (2006) The argonautes. Cold Spring Harb Symp Quant Biol, 71. pp. 67-72. ISSN 1943-4456 (Electronic) 0091-7451 (Linking)

K

Karpova, A. Y., Tervo, D. G., Gray, N. W., Svoboda, K. (December 2005) Rapid and reversible chemical inactivation of synaptic transmission in genetically targeted neurons. Neuron, 48 (5). pp. 727-35. ISSN 0896-6273 (Print)

Kumar, Rajeev, Conklin, Douglas S., Mittal, Vivek (October 2003) High-throughput selection of effective RNAi probes for gene silencing. Genome Research, 13 (10). pp. 2333-2340. ISSN 1088-9051

Kuscu, C., Zaratiegui, M., Kim, H. S., Wah, D. A., Martienssen, R. A., Schalch, T., Joshua-Tor, L. (January 2014) CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing. Proceedings of the National Academy of Sciences of the United States of America, 111 (5). pp. 1795-1800. ISSN 0027-8424 (Public Dataset)

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Li, Q., Fazly, A. M., Zhou, H., Huang, S., Zhang, Z., Stillman, B. (October 2009) The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents. Plos Genetics, 5 (10). e1000684. ISSN 1553-7390

Lippman, Z., Martienssen, R. A. (September 2004) The role of RNA interference in heterochromatic silencing. Nature, 431 (7006). pp. 364-70. ISSN 1476-4687 (Electronic)

Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., Song, J. J., Hammond, S. M., Joshua-Tor, L., Hannon, G. J. (September 2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science, 305 (5689). pp. 1437-41. ISSN 1095-9203 (Electronic)

Liu-Sullivan, N., Zhang, J., Bakleh, A., Marchica, J., Li, J., Siolas, D., Laquerre, S., Degenhardt, Y. Y., Wooster, R., Chang, K., Hannon, G. J., Powers, S. (December 2011) Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1). Oncotarget, 2 (12). pp. 1254-64. ISSN 1949-2553 (Electronic) 1949-2553 (Linking)

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Maestro, R., Dei Tos, A. P., Hamamori, Y., Krasnokutsky, S., Sartorelli, V., Kedes, L., Doglioni, C., Beach, D. H., Hannon, G. J. (September 1999) Twist is a potential oncogene that inhibits apoptosis. Genes and Development, 13 (17). pp. 2207-17. ISSN 0890-9369

Martienssen, R. (July 1996) Epigenetic phenomena: Paramutation and gene silencing in plants. Current Biology, 6 (7). pp. 810-813. ISSN 0960-9822

Martienssen, R., Lippman, Z., May, B., Ronemus, M., Vaughn, M. (2004) Transposons, tandem repeats, and the silencing of imprinted genes. Cold Spring Harbor symposia on quantitative biology, 69. pp. 371-9. ISSN 0091-7451 (Print)0091-7451 (Linking)

Matapurkar, A., Lazebnik, Y. (December 2006) Requirement of cytochrome c for apoptosis in human cells. Cell Death Differ, 13 (12). pp. 2062-7. ISSN 1350-9047 (Print)

McCaffrey, A. P., Meuse, L., Pham, T. T. T., Conklin, D. S., Hannon, G. J., Kay, M. A. (July 2002) Gene expression - RNA interference in adult mice. Nature, 418 (6893). pp. 38-39. ISSN 0028-0836

Mittal, V. (May 2004) Improving the efficiency of RNA interference in mammals. Nat Rev Genet, 5 (5). pp. 355-65.

Murchison, E. P., Partridge, J. F., Tam, O. H., Cheloufi, S., Hannon, G. J. (August 2005) Characterization of Dicer-deficient murine embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America, 102 (34). pp. 12135-40. ISSN 0027-8424

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Narita, M., Nunez, S., Heard, E., Narita, M., Lin, A. W., Hearn, S. A., Spector, D. L., Hannon, G. J., Lowe, S. W. (June 2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell, 113 (6). pp. 703-716. ISSN 0092-8674

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Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J., Conklin, D. S. (2002) Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes and Development, 16 (8). pp. 948-958. ISSN 08909369 (ISSN)

Paddison, P. J., Caudy, A. A., Sachidanandam, R., Hannon, G. J. (2004) Short hairpin activated gene silencing in mammalian cells. In: RNA Interference, Editing and Modification: methods and protocols. Methods Mol Biol, 265 . Springer, pp. 85-100.

Paddison, P. J., Silva, J. M., Conklin, D. S., Schlabach, M., Li, M., Aruleba, S., Balija, V., O'Shaughnessy, A., Gnoj, L., Scobie, K., Chang, K., Westbrook, T., Cleary, M., Sachidanandam, R., McCombie, W. R., Elledge, S. J., Hannon, G. J. (March 2004) A resource for large-scale RNA-interference-based screens in mammals. Nature, 428 (6981). pp. 427-31. ISSN 1476-4687 (Electronic)

Parent, J. S., Jauvion, V., Bouche, N., Beclin, C., Hachet, M., Zytnicki, M., Vaucheret, H. (September 2015) Post-transcriptional gene silencing triggered by sense transgenes involves uncapped antisense RNA and differs from silencing intentionally triggered by antisense transgenes. Nucleic Acids Res, 43 (17). pp. 8464-75. ISSN 1362-4962 (Electronic)0305-1048 (Linking)

R

Roca, X., Krainer, A. R. (March 2009) A splicing component adapted to gene silencing. Nat Biotechnol, 27 (3). pp. 250-1. ISSN 1546-1696 (Electronic)1087-0156 (Linking)

Rossmann, M. P., Luo, W., Tsaponina, O., Chabes, A., Stillman, B. (April 2011) A Common Telomeric Gene Silencing Assay Is Affected by Nucleotide Metabolism. Molecular Cell, 42 (1). pp. 127-136. ISSN 1097-2765

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Sachidanandam, R. (September 2004) RNAi: design and analysis. Curr Protoc Bioinformatics, Chapte. Unit 12.3. ISSN 1934-340X (Electronic)

Sachidanandam, Ravi (June 2005) RNAi as a bioinformatics consumer. Brief Bioinform, 6 (2). pp. 146-62. ISSN 1467-5463 (Print)

Schalch, T., Job, G., Shanker, S., Partridge, J., Joshua-Tor, L. (2011) The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Molecular Biology of the Cell, 22. ISSN 1059-1524

Silva, J., Chang, K., Hannon, G. J., Rivas, F. V. (November 2004) RNA-interference-based functional genomics in mammalian cells: reverse genetics coming of age. Oncogene, 23 (51). pp. 8401-9. ISSN 0950-9232 (Print)

Silva, J. M., Mizuno, H., Brady, A., Lucito, R., Hannon, G. J. (April 2004) RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells. Proc Natl Acad Sci U S A, 101 (17). pp. 6548-52. ISSN 0027-8424 (Print)

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Vaughn, M. W., Martienssen, R. A. (March 2005) Finding the right template: RNA Pol IV, a plant-specific RNA polymerase. Mol Cell, 17 (6). pp. 754-6. ISSN 1097-2765 (Print)

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Watts, J. A., Zhang, C. L., Klein-Szanto, A. J., Kormish, J. D., Fu, J., Zhang, M. Q., Zaret, K. S. (September 2011) Study of FoxA Pioneer Factor at Silent Genes Reveals Rfx-Repressed Enhancer at Cdx2 and a Potential Indicator of Esophageal Adenocarcinoma Development. PLoS Genetics, 7 (9). ISSN 1553-7390

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Xue, W., Kitzing, T., Roessler, S., Zuber, J., Krasnitz, A., Schultz, N., Revill, K., Weissmueller, S., Rappaport, A. R., Simon, J., Zhang, J., Luo, W. J., Hicks, J., Zender, L., Wang, X. W., Powers, S., Wigler, M., Lowe, S. W. (May 2012) A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proceedings of the National Academy of Sciences of the United States of America, 109 (21). pp. 8212-8217. ISSN 0027-8424

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Yang, M., Haase, A. D., Huang, F. K., Coulis, G., Rivera, K. D., Dickinson, B. C., Chang, C. J., Pappin, D. J., Neubert, T. A., Hannon, G. J., Boivin, B., Tonks, N. K. (August 2014) Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence. Mol Cell, 55 (5). pp. 782-790. ISSN 1097-2765

Yang, Zhaolin, Wu, Xiaoli S, Wei, Yiliang, Polyanskaya, Sofya A, Iyer, Shruti V, Jung, Moonjung, Lach, Francis P, Adelman, Emmalee R, Klingbeil, Olaf, Milazzo, Joseph P, Kramer, Melissa, Demerdash, Osama E, Chang, Kenneth, Goodwin, Sara, Hodges, Emily, McCombie, W Richard, Figueroa, Maria E, Smogorzewska, Agata, Vakoc, Christopher R (April 2021) Transcriptional silencing of ALDH2 confers a dependency on Fanconi anemia proteins in acute myeloid leukemia. Cancer Discovery. ISSN 2159-8274

Yu, Y., Gu, J., Jin, Y., Luo, Y., Preall, J. B., Ma, J., Czech, B., Hannon, G. J. (October 2015) Panoramix enforces piRNA-dependent cotranscriptional silencing. Science, 350 (6258). pp. 339-42. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

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Zaiss, A. K., Zuber, J., Chu, C., Machado, H. B., Jiao, J., Catapang, A. B., Ishikawa, T. O., Gil, J. S., Lowe, S. W., Herschman, H. R. (July 2014) Reversible Suppression of Cyclooxygenase 2 (COX-2) Expression In Vivo by Inducible RNA Interference. PLoS One, 9 (7). e101263. ISSN 1932-6203

Zebell, Sophia (March 2021) Gene body silencing parental alleles for vigorous hybrid rice. Plant Physiology, 186 (2). pp. 822-823. ISSN 0032-0889

Zhang, T., Wu, Y. C., Mullane, P., Ji, Y. J., Liu, H., He, L., Arora, A., Hwang, H. Y., Alessi, A. F., Niaki, A. G., Periz, G., Guo, L., Wang, H., Elkayam, E., Joshua-Tor, L., Myong, S., Kim, J. K., Shorter, J., Ong, S. E., Leung, A. K. L., Wang, J. (March 2018) FUS Regulates Activity of MicroRNA-Mediated Gene Silencing. Mol Cell, 69 (5). 787-801.e8. ISSN 1097-2765 (Public Dataset)