Items where Community is "Theses"

Tang, Ziqi (April 2024) Exploring the Representational Power of Genomic Deep Learning Models. PhD thesis, Cold Spring Harbor Laboratory.

Ciren, Danielle (February 2024) Decoding cis-regulatory control and evolution of conserved and divergent phenotypes in plants. PhD thesis, Cold Spring Harbor Laboratory.

Dussauze, Marie (February 2024) Sensorimotor neural representations in the olfactory cortex. PhD thesis, Cold Spring Harbor Laboratory.

Ziyi, Mo (January 2024) Scalable and robust deep-learning methods power evolutionary-genetic studies of biobank-scale population genomic data. PhD thesis, Cold Spring Harbor Laboratory.

Werner, Jonathan M (December 2023) Transcriptomic approaches for investigating developmental lineage: exploiting the X-chromosome as a marker for lineage specification and quantifying the lineage fidelity of neural organoid systems. PhD thesis, Cold Spring Harbor Laboratory.

Wunderlich, Cole (September 2023) Quantifying Transposable Element Expression in Single-Cell RNA Sequencing Data. PhD thesis, Cold Spring Harbor Laboratory.

Hu, Yuzhao (August 2023) Role of cryptochromes in chromatin remodeling and DNA damage repair. PhD thesis, Cold Spring Harbor Laboratory.

Wang, Julia Huiming (June 2023) Interpretable Brain State Manifold for Characterizing Heterogeneity. PhD thesis, Cold Spring Harbor Laboratory.

Ergin, Ilgin (May 2023) Metabolic regulation of anti-tumor immunity. PhD thesis, Cold Spring Harbor Laboratory.

Pagliaro, Alexa H (May 2023) A disrupted parvalbumin network state impairs maternal behavior in a mouse model of Rett Syndrome. PhD thesis, Cold Spring Harbor Laboratory.

Ruiz-Ortiz, Jenelys (May 2023) Characterizing Models to Study Cellular Composition Changes in Response to Pregnancy Hormones in the Human Mammary Gland. PhD thesis, Cold Spring Harbor Laboratory.

Boyle, Sara (May 2023) The Central Amygdala Encodes Nutritional Properties and Modulates Weight Gain. PhD thesis, Cold Spring Harbor Laboratory.

Yuan, Chengxiang (March 2023) Applications of oligonucleotide ligation in sequencing. PhD thesis, Cold Spring Harbor Laboratory.

Maia-Silva, Diogo (March 2023) MECHANISMS OF GENE TRANSCRIPTION BY TP63 AND THE MEDIATOR COMPLEX IN SQUAMOUS PANCREATIC CANCER. PhD thesis, Cold Spring Harbor Laboratory.

Aguirre, Lyndsey (March 2023) Dissection of Quantitative Epistasis in Tomato Meristem Development. PhD thesis, Cold Spring Harbor Laboratory.

Corona, Alberto (March 2023) Sex-dependent neural activity underlying parenting behavior in mice. PhD thesis, Cold Spring Harbor Laboratory.

Lakhani, Asad A (March 2023) The Role of Recurrently Observed Aneuploidy in Tumorigenesis. PhD thesis, Cold Spring Harbor Laboratory.

Hanasoge Somasundara, Amritha Varshini (November 2022) Investigating the role of changes to the mammary gland immune microenvironment in pregnancy-induced oncoprotection. PhD thesis, Cold Spring Harbor Laboratory.

Johnson, David (July 2022) ELUCIDATING THE EFFECTS OF DEPLETING BRPF1 IN HUMAN GBM. PhD thesis, Cold Spring Harbor Laboratory.

O’Neill, Kathryn Shea (June 2022) Investigations into the contribution of retrotransposon activation in neurodegenerative disease. PhD thesis, Cold Spring Harbor Laboratory.

Gegenhuber, Bruno (April 2022) Epigenomic organization and activation of brain sex differences. PhD thesis, Cold Spring Harbor Laboratory.

Shen, Luqun (April 2022) Perceptual Categorization and Neural Representations of Vocal Stimuli. PhD thesis, Cold Spring Harbor Laboratory.

Krasniak, Christopher (April 2022) Mesoscale imaging, inactivation, and collaboration in a standardized visual decision-making task. PhD thesis, Cold Spring Harbor Laboratory.

Yan, Ran (March 2022) Tumor immunogenicity and plasticity of cancer-associated fibroblasts orchestrate the host immune response to mouse pancreatic cancer. PhD thesis, Cold Spring Harbor Laboratory.

Sroka, Martyna W (March 2022) Myodifferentiation of Rhabdomyosarcoma. PhD thesis, Cold Spring Harbor Laboratory.

Harris, Benjamin D (October 2021) Atlas level scRNAseq analysis reveals the functional landscape of cell types. PhD thesis, Cold Spring Harbor Laboratory.

Bibel, Brianna L (October 2021) Regulating the regulator: Phosphorylation-mediated regulation of the RNAi effector protein Argonaute. PhD thesis, Cold Spring Harbor Laboratory.

Lu, Shaina (September 2021) The replicability of spatially-resolved transcriptomics for modern neuroscience. PhD thesis, Cold Spring Harbor Laboratory.

Berube, Benjamin (August 2021) Epigenetic Control of Meiotic Recombination and Drive. PhD thesis, Cold Spring Harbor Laboratory.

Meze, Katarina (July 2021) Mechanism of Structured RNA Degradation by the Human Exonuclease Dis3L2. PhD thesis, Cold Spring Harbor Laboratory.

Nowlan, Alexandra C (April 2021) An amygdalo-cortical circuit for multisensory processing in maternal behavior. PhD thesis, Cold Spring Harbor Laboratory.

Polyanskaya, Sofya A (July 2020) A Nuclear Phosphatase-Kinase Signaling Complex That Supports Acute Myeloid Leukemia. PhD thesis, Cold Spring Harbor Laboratory.

Zhang, Anqi (July 2020) Representations in Rodent Primary Visual Cortex During Visual Discrimination. PhD thesis, Cold Spring Harbor.

Gutbrod, Michael J. (November 2019) Chromosomal Functions of RNA Interference and Small RNAs in Early Mammalian Development. PhD thesis, Cold Spring Harbor Laboratory.

Giovanniello, Jacqueline (October 2019) Characterizing amygdala-pallidal circuitry and its role in behavioral dysfunction in a 16p11.2 microdeletion model of ASD. PhD thesis, Cold Spring Harbor Laboratory.

Maiorino, L. (August 2019) Identification Of Cancer-Cell Intrinsic And Host-Mediated Cellular Mechanisms Of Metastasis Through Intravital Imaging. PhD thesis, Cold Spring Harbor Laboratory.

Bružas, Emilis (August 2019) The Role Of Immunity In Breast Cancer Dormancy And Recurrence. PhD thesis, Cold Spring Harbor Laboratory.

Yordanov, Georgi Nenov (July 2019) Myc and Spdef: two transcription factors hijacked by pancreatic cancer. PhD thesis, Cold Spring Harbor.

Pisupati, Sashank (April 2019) A value-based explanation for lapses in perceptual decisions. PhD thesis, Cold Spring Harbor.

Cazakoff, B. N. (April 2017) State and Learning Dependent Changes in Olfactory Granule Cells. PhD thesis, Cold Spring Harbor Laboratory.

Delas Vives, M.J. (March 2017) Role of long noncoding RNAs in hematopoiesis. PhD thesis, Cold Spring Harbor Laboratory.

Hohmann, A. F. (May 2016) Function and Inhibition of BRD9 in Acute Myeloid Leukemia Cells. PhD thesis, Cold Spring Harbor Laboratory.

Aboukhalil, Robert (March 2016) Elucidating Cancer Evolution using Single-Cell Sequencing and Comparative Genomics. PhD thesis, Cold Spring Harbor Laboratory.

Krug, L. (March 2016) The Role of Transposable Elements in TDP-43-Mediated Neurodegeneration. PhD thesis, Cold Spring Harbor Laboratory.

Peikon, I. D. (November 2014) Encoding of neural circuit information into DNA. PhD thesis, Cold Spring Harbor Laboratory.

Delevich, K.M. (October 2014) Synaptic effects of disrupted-in-schizophrenia 1 loss-of-function in the medial prefrontal cortex and thalamofrontal feedforward inhibitory circuit. PhD thesis, Cold Spring Harbor Laboratory.

Zepeda-Mendoza, C. J. (September 2014) Impact of copy number variation on chromatin interactions at the mouse 4e2 chromosome region. PhD thesis, Cold Spring Harbor Laboratory.

Castel, S. E. (September 2014) Transcriptional regulation in the context of DNA replication by RNA interference in fission yeast. PhD thesis, Cold Spring Harbor Laboratory.

Tasdemir, N. (August 2014) Investigating the role of Brd4 in cellular senescence and normal tissue homeostatsis. PhD thesis, Cold Spring Harbor Laboratory.

Wagenblast, E. (August 2014) A molecular characterization of breast cancer progression, including onset, tumor growth and metastasis. PhD thesis, Cold Spring Harbor Laboratory.

Bekritsky, M. (August 2014) Detecting de novo microsatellite mutations in a population of families with sporadic autism. PhD thesis, Cold Spring Harbor Laboratory.

Weissmueller, S. (July 2014) The impact of chromosome 17p alterations on cancer. PhD thesis, Cold Spring Harbor Laboratory.

Batut, Philippe (April 2014) Promoter Evolution in Drosophila: Non-Coding Transcription & Transposon-Driven Innovation. PhD thesis, Cold Spring Harbor Laboratory.

Wasik, Kaja (April 2014) Unusual aspects of piRNA pathways in mice and flatworms. PhD thesis, Cold Spring Harbor Laboratory.

Liberatore, Katie (April 2014) Investigating the roles of gene dosage and stem cell maintenance in the regulation of plant shoot and inflorescence architecture. PhD thesis, Cold Spring Harbor Laboratory.

Znamenskiy, Petr (March 2014) Role of corticostriatal projections in auditory discrimination. PhD thesis, Cold Spring Harbor Laboratory.

Eckersley-Maslin, Melanie A. (January 2014) Characteristics of random monoallelic gene expression during embryonic stem cell differentiation. PhD thesis, Cold Spring Harbor Laboratory.

Sanders, Joshua (January 2014) A computational framework for understanding decision confidence. PhD thesis, Cold Spring Harbor Laboratory.

Perova, Zinaida (January 2014) Synaptic changes in the medial prefrontal cortex in susceptibility and resilience to stress. PhD thesis, Cold Spring Harbor Laboratory.

Plavskin, Yevgeniy (August 2013) Regulation of the auxin response by an ancient small RNA pathway. PhD thesis, Cold Spring Harbor Laboratory.

Pautler, Michael (August 2013) Meristem size and determinacy in Maize. PhD thesis, Cold Spring Harbor Laboratory.

Kudla, Marek (August 2013) Quantitative description of microRNA target site occupancy in mouse embryonic stem cells and derived cells of neuronal lineage. PhD thesis, Cold Spring Harbor Laboratory.

Guzzardo, Paloma M. (April 2013) Identification and characterization of novel components of the Drosophila piRNA pathway. PhD thesis, Cold Spring Harbor Laboratory.

Ebbesen, Saya H. (April 2013) RNAi Mouse Models of Breast Cancer Tumor Suppressor Genes. PhD thesis, Cold Spring Harbor Laboratory.

Bodnar, M. S. (March 2013) The Dynamics of Pluripotency Genes Upon Differentiation of Mouse Embryonic Stem Cells. PhD thesis, Cold Spring Harbor Laboratory.

Calarco, Joseph P. (2013) Chromatin Dynamics during Germline Development. PhD thesis, Cold Spring Harbor Laboratory.

Pineda, Maria L (September 2012) Substrate specificity of receptor tyrosine kinases is critical for selective signaling. PhD thesis, Cold Spring Harbor Laboratory.

Gruntman, Eyal (July 2012) Integration Properties of Kenyon Cells in the Drosophila melanogaster Mushroom Bodies. PhD thesis, Cold Spring Harbor Laboratory.

Wang, Zhenxun (June 2012) The mechanism and manipulation of PK-M alternative splicing. PhD thesis, Cold Spring Harbor Laboratory.

Nakasone, Elizabeth (March 2012) A Stromal CCL2/CCR2 Signaling Axis Regulates Chemotherapeutic Response in a Mouse Model of Breast Cancer. PhD thesis, Cold Spring Harbor Laboratory.

Honegger, Kyle S. (March 2012) Neural coding in the Drosophila Mushroom Body. PhD thesis, Cold Spring Harbor Laboratory.

Finigan, P. (August 2011) The origin of novel phenotypic variation in Arabidopsis allopolyploids. PhD thesis, Cold Spring Harbor Laboratory.

Scuoppo, C. (March 2011) Architectural Models of Tumor Suppression in Lymphoma. PhD thesis, Cold Spring Harbor Laboratory.

Rappaport, A. R. (2011) Dissecting tumor suppressor and tumor maintenance genes in poor prognosis AML. PhD thesis, Cold Spring Harbor Laboratory.

Rollins, F. (2011) The genetics and epigenetics of erlotinib resistance in non-small cell lung cancer. PhD thesis, Cold Spring Harbor Laboratory.

Collins, G. A. (March 2010) Activator Turnover and Proteolysis In Transcriptional Activation. PhD thesis, Cold Spring Harbor Laboratory.

Leung, A. (March 2010) Regulation of Chromatin by Histone H2B Ubiquitylation. PhD thesis, Cold Spring Harbor Laboratory.

Tam, O. H. (February 2010) Characterization of small RNA populations and DNA methylation in mammalian development. PhD thesis, Cold Spring Harbor Laboratory.

Erlich, Y. (February 2010) Compressed Sequencing. PhD thesis, Cold Spring Harbor Laboratory.

Fregoso, O. I. (February 2010) Elucidating the Functions of Splicing Regulatory Proteins Through the Use of High-Throughput Proteomics. PhD thesis, Cold Spring Harbor Laboratory.

Malone, C. D. (February 2010) Evolution, Inheritance and Specialization of Transposon Control Pathways in Drosophila. PhD thesis, Cold Spring Harbor Laboratory.

Simpson, D. R. (February 2010) Regulation of Myc-induced apoptosis in the mammary epithelia. PhD thesis, Cold Spring Harbor Laboratory.

Pai, S. S. (January 2010) Neuroanatomical Localization of Timing-Specific Brain Loci in the Rat. PhD thesis, Cold Spring Harbor Laboratory.

McJunkin, K. (2010) Inducible RNAi targeting essential genes. PhD thesis, Cold Spring Harbor Laboratory.

Makino, H. (2010) A thesis by Hiroshi Makino. PhD thesis, Cold Spring Harbor Laboratory.

Wilusz, J. E. (March 2009) 3’ end processing of long nuclear-retained non-coding RNAs yields tRNA-like small RNAs. PhD thesis, Cold Spring Harbor Laboratory.

John, K.A. (March 2009) Characterization of the role of DOCK7 in neuronal development. PhD thesis, Cold Spring Harbor Laboratory.

Chitwood, D. H. (2009) Patterning in Leaves via a Cascade of Small RNAs. PhD thesis, Cold Spring Harbor Laboratory.

Chiu, S. L. (July 2008) The role of insulin receptor in the development of neuronal structure and function. PhD thesis, Cold Spring Harbor Laboratory.

Harvey, C. D. (February 2008) Dynamics of Plasticity and Signaling at Individual Synapses. PhD thesis, Cold Spring Harbor Laboratory.

Wei, W. (February 2008) The Interplay Between Amyloid-β and Neural Activity. PhD thesis, Cold Spring Harbor Laboratory.

Girard, A. (February 2008) Mammalian Piwi proteins and transposon silencing in the male germline. PhD thesis, Cold Spring Harbor Laboratory.

Bolduc, F. V. (October 2007) Role of Drosophila Fragile X mental retardation protein and the RNA interference pathway in Drosophila learning and memory. PhD thesis, Cold Spring Harbor Laboratory.

Tervo, D. G. (March 2007) Development of Molecular Systems for the Inactivation of Synaptic Transmission. PhD thesis, Cold Spring Harbor Laboratory.

Feierstein, C. E. (February 2007) Representation of goals, actions and outcomes in rat orbitofrontal cortex. PhD thesis, Cold Spring Harbor Laboratory.

Asari, H. (2007) Auditory System Characterization. PhD thesis, Cold Spring Harbor Laboratory.

Chen, B. L. (2007) Neuronal Network of C. elegans: from Anatomy to Behavior. PhD thesis, Cold Spring Harbor Laboratory.

Bish, Rebecca A. (2007) A Novel Role for the Ubiquitin-Binding Zinc Finger Domain in DNA Repair. PhD thesis, Cold Spring Harbor Laboratory.

Burgess, D. J. (2007) RNAi Genetic Screens for Chemotherapy Response Modifier Genes. PhD thesis, Cold Spring Harbor Laboratory.

Kopec, C. D. (April 2006) AMPA Receptor Trafficking and their Effect on Spine Enlargement during Long-term Potentiation. PhD thesis, Cold Spring Harbor Laboratory.

Ewald, R. C. (April 2006) NMDA receptor subtypes and dendritic arbor morphology. PhD thesis, Cold Spring Harbor Laboratory.

Mangone, M. (March 2006) Analysis of the HCF-1 basic region and its role in sustaining cell proliferation. PhD thesis, Cold Spring Harbor Laboratory.

Cormier, C. (2006) Alternative Apoptotic Pathways in Cancer Cells. PhD thesis, Cold Spring Harbor Laboratory.

Chakraborty, S. (November 2005) Analysis and Modeling of Neural Connectivity in a Short Term Memory System. PhD thesis, Cold Spring Harbor Laboratory.

Muratani, M. (April 2005) Regulation of Gene Expression by the Ubiquitin-Proteasome System. PhD thesis, Cold Spring Harbor Laboratory.

Ezhkova, E. (March 2005) Role of the Proteasome in Gene Control. PhD thesis, Cold Spring Harbor Laboratory.

Song, J. J. (March 2005) STRUCTURAL AND BIOCHEMICAL STUDIES OF ARGONAUTE REVEAL THE SLICING MECHANISM OF RISC – RNAI EFFECTOR COMPLEX. PhD thesis, Cold Spring Harbor Laboratory.

Lippman, Z. B. (December 2004) Transposons, heterochromatin, and epigenetic landscapes in Arabidopsis thaliana. PhD thesis, Cold Spring Harbor Laboratory.

Thomas, E. E. (April 2004) Exploring Repetitive Sequences in the Human Genome. PhD thesis, Cold Spring Harbor Laboratory.

Rial Verde, E. M. (April 2004) THE ROLE OF THE IMMEDIATE-EARLY GENE ARC IN SYNAPTIC TRANSMISSION. PhD thesis, Cold Spring Harbor Laboratory.

Paddison, Patrick J. (2004) RNA interference in mammals: the quest for illuminating gene function. PhD thesis, Cold Spring Harbor Laboratory.

Tolia, N. H. (2004) STRUCTURAL AND BIOCHEMICAL STUDIES OF EBA-175, A PROTEIN THAT MEDIATES ERYTHROCYTE INVASION BY THE MALARIA PARASITE PLASMODIUM FALCIPARUM. PhD thesis, Cold Spring Harbor Laboratory.

Hall, I. M. (November 2003) A Role for RNA Interference in Heterochromatic Silencing and Chromosome Dynamics. PhD thesis, Cold Spring Harbor Laboratory.

Caudy, A. A. (2003) Mechanism and applications of RNAi. PhD thesis, Cold Spring Harbor Laboratory.