Browse by CSHL Author

Paper

Schaniel, C., Ang, Y. S., Ratnakumar, K., Cormier, C., James, T., Bernstein, E., Lemischka, I. R., Paddison, P. J. (December 2009) Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells, 27 (12). pp. 2979-2991.

Gadue, P., Huber, T. L., Paddison, P. J., Keller, G. M. (2006) Wnt and TGF-ß signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America, 103 (45). pp. 16806-16811. ISSN 00278424

Silva, J. M., Li, M. Z., Chang, K., Ge, W., Golding, M. C., Rickles, R. J., Siolas, D., Hu, G., Paddison, P. J., Schlabach, M. R., Sheth, N., Bradshaw, J., Burchard, J., Kulkarni, A., Cavet, G., Sachidanandam, R., McCombie, W. R., Cleary, M. A., Elledge, S. J., Hannon, G. J. (November 2005) Second-generation shRNA libraries covering the mouse and human genomes. Nat Genet, 37 (11). pp. 1281-8.

Siolas, D., Lerner, C., Burchard, J., Ge, W., Linsley, P. S., Paddison, P. J., Hannon, G. J., Cleary, M. A. (February 2005) Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol, 23 (2). pp. 227-31. ISSN 1087-0156 (Print)

Cleary, M. A., Kilian, K., Wang, Y., Bradshaw, J., Cavet, G., Ge, W., Kulkarni, A., Paddison, P. J., Chang, K., Sheth, N., Leproust, E., Coffey, E. M., Burchard, J., McCombie, W. R., Linsley, P., Hannon, G. J. (December 2004) Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis. Nat Methods, 1 (3). pp. 241-8.

Paddison, P. J., Cleary, M., Silva, J. M., Chang, K., Sheth, N., Sachidanandam, R., Hannon, G. J. (November 2004) Cloning of short hairpin RNAs for gene knockdown in mammalian cells. Nat Methods, 1 (2). pp. 163-7. ISSN 1548-7091 (Print)

Paddison, P. J., Silva, J. M., Conklin, D. S., Schlabach, M., Li, M., Aruleba, S., Balija, V., O'Shaughnessy, A., Gnoj, L., Scobie, K., Chang, K., Westbrook, T., Cleary, M., Sachidanandam, R., McCombie, W. R., Elledge, S. J., Hannon, G. J. (March 2004) A resource for large-scale RNA-interference-based screens in mammals. Nature, 428 (6981). pp. 427-31. ISSN 1476-4687 (Electronic)

Hemann, M. T., Fridman, J. S., Zilfou, J. T., Hernando, E., Paddison, P. J., Cordon-Cardo, C., Hannon, G. J., Lowe, S. W. (March 2003) An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nature Genetics, 33 (3). pp. 396-400. ISSN 1061-4036

Paddison, P. J., Hannon, G. J. (2003) siRNAs and shRNAs: Skeleton keys to the human genome. Current Opinion in Molecular Therapeutics, 5 (3). pp. 217-224. ISSN 14648431 (ISSN)

Paddison, P. J., Hannon, G. J. (2002) RNA interference: The new somatic cell genetics? Cancer Cell, 2 (1). pp. 17-23. ISSN 15356108 (ISSN)

Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J., Conklin, D. S. (2002) Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes and Development, 16 (8). pp. 948-958. ISSN 08909369 (ISSN)

Paddison, P. J., Caudy, A. A., Hannon, G. J. (2002) Stable suppression of gene expression by RNAi in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 99 (3). pp. 1443-1448. ISSN 00278424 (ISSN)

Book Section

Paddison, P. J. (2008) RNA interference in mammalian cell systems. In: RNA Interference. Curr Top Microbiol Immunol, 320 . Springer Verlag, Berlin; New York, pp. 1-19. ISBN 978-3-540-75156-4

Paddison, Patrick J., Hannon, Gregory J. (2004) RNA Interference in Mammals: Journey to the Center of Human Disease. In: Molecular Cancer Therapeutics. John Wiley & Sons, Inc., Hoboken, NJ, pp. 55-72. ISBN 9780471656166

Paddison, P. J., Caudy, A. A., Sachidanandam, R., Hannon, G. J. (2004) Short hairpin activated gene silencing in mammalian cells. In: RNA Interference, Editing and Modification: methods and protocols. Methods Mol Biol, 265 . Springer, pp. 85-100.

Book

Paddison, P. J., Vogt, P. K., eds. (2008) RNA Interference. Curr Top Microbiol Immunol, 320 . Springer Verlag, Berlin; New York. ISBN 978-3-540-75156-4

Thesis

Paddison, Patrick J. (2004) RNA interference in mammals: the quest for illuminating gene function. PhD thesis, Cold Spring Harbor Laboratory.