Browse by CSHL Author

Paper

Koulakov, A, Lazebnik, Y (2012) The problem of colliding networks and its relation to cell fusion and cancer. Biophysical Journal, 103 (9). pp. 2011-2020.

Gottesman, A., Milazzo, J., Lazebnik, Y. (October 2010) V-fusion: a convenient, nontoxic method for cell fusion. Biotechniques, 49 (4). pp. 747-50. ISSN 1940-9818 (Electronic) 0736-6205 (Linking)

Lazebnik, Y. (April 2010) What are the hallmarks of cancer? Nature Reviews Cancer, 10. pp. 232-233.

Duelli, D., Lazebnik, Y. (December 2007) Cell-to-cell fusion as a link between viruses and cancer. Nat Rev Cancer, 7 (12). pp. 968-76. ISSN 1474-1768 (Electronic)

Yuneva, M., Zamboni, N., Oefner, P., Sachidanandam, R., Lazebnik, Y. (July 2007) Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. J Cell Biol, 178 (1). pp. 93-105. ISSN 0021-9525 (Print)

Duelli, D. M., Padilla-Nash, H. M., Berman, D., Murphy, K. M., Ried, T., Lazebnik, Y. (March 2007) A virus causes cancer by inducing massive chromosomal instability through cell fusion. Current Biology, 17 (5). pp. 431-7. ISSN 0960-9822 (Print)

Matapurkar, A., Lazebnik, Y. (December 2006) Requirement of cytochrome c for apoptosis in human cells. Cell Death Differ, 13 (12). pp. 2062-7. ISSN 1350-9047 (Print)

Soengas, M. S., Gerald, W. L., Cordon-Cardo, C., Lazebnik, Y., Lowe, S. W. (2006) Apaf-1 expression in malignant melanoma. Cell Death and Differentiation, 13 (2). pp. 352-353. ISSN 13509047

Duelli, D. M., Hearn, S., Myers, M. P., Lazebnik, Y. (November 2005) A primate virus generates transformed human cells by fusion. J Cell Biol, 171 (3). pp. 493-503. ISSN 0021-9525 (Print)

Dorstyn, L., Mills, K., Lazebnik, Y., Kumar, S. (November 2004) The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells. Journal of Cell Biology, 167 (3). pp. 405-410. ISSN 0021-9525

Svingen, P. A., Loegering, D., Rodriquez, J., Meng, X. W., Mesner, P. W., Holbeck, S., Monks, A., Krajewski, S., Scudiero, D. A., Sausville, E. A., Reed, J. C., Lazebnik, Y. A., Kaufmann, S. H. (October 2004) Components of the cell death machine and drug sensitivity of the National Cancer Institute cell line panel. Clinical Cancer Research, 10 (20). pp. 6807-6820. ISSN 1078-0432

Duelli, Dominik, Lazebnik, Yuri (2003) Cell fusion: a hidden enemy? Cancer Cell, 3 (5). pp. 445-448. ISSN 1535-6108

Belov, George A., Romanova, Lyudmila I., Tolskaya, Elena A., Kolesnikova, Marina S., Lazebnik, Yuri A., Agol, Vadim I. (2003) The major apoptotic pathway activated and suppressed by poliovirus. Journal of Virology, 77 (1). pp. 45-56. ISSN 0022-538X

Lassus, P., Rodriguez, J., Lazebnik, Y. (August 2002) Confirming specificity of RNAi in mammalian cells. Sci STKE, 2002 (147). pl13. ISSN 1525-8882 (Electronic)1525-8882 (Linking)

Lazebnik, Yuri (2002) Can a biologist fix a radio?--Or, what I learned while studying apoptosis. Cancer Cell, 2 (3). pp. 179-182. ISSN 1535-6108

Nahle, Zaher, Polakoff, Julia, Davuluri, Ramana V., McCurrach, Mila E., Jacobson, Matthew D., Narita, Masashi, Zhang, Michael Q., Lazebnik, Yuri, Bar-Sagi, Dafna, Lowe, Scott W. (2002) Direct coupling of the cell cycle and cell death machinery by E2F. Nature Cell Biology, 4 (11). pp. 859-864. ISSN 1465-7392

Pistritto, G., Jost, M., Srinivasula, S. M., Baffa, R., Poyet, J. L., Kari, C., Lazebnik, Y., Rodeck, U., Alnemri, E. S. (2002) Expression and transcriptional regulation of caspase-14 in simple and complex epithelia. Cell Death and Differentiation, 9 (9). pp. 995-991006. ISSN 1350-9047

Hegde, Ramesh, Srinivasula, Srinivasa M., Zhang, ZhiJia, Wassell, Richard, Mukattash, Rula, Cilenti, Lucia, DuBois, Garrett, Lazebnik, Yuri, Zervos, Antonis S., Fernandes-Alnemri, Teresa, Alnemri, Emad S. (2002) Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction. Journal of Biological Chemistry, 277 (1). pp. 432-438. ISSN 0021-9258

Lassus, Patrice, Opitz-Araya, Ximena, Lazebnik, Yuri (2002) Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science, 297 (5585). pp. 1352-1354. ISSN 1095-9203

Soengas, M. S., Capodieci, P., Polsky, D., Mora, J., Esteller, M., Opitz-Araya, X., McCombie, R., Herman, J. G., Gerald, W. L., Lazebnik, Y. A., Cordon-Cardo, C., Lowe, S. W. (2001) Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature, 409 (6817). pp. 207-211. ISSN 0028-0836

Lazebnik, Y. (2001) Why do regulators of apoptosis look like bacterial toxins? Current Biology, 11 (19). pp. 767-768. ISSN 0960-9822

Rodriguez, Joe, Chen, Hsu-Hsin, Lin, Shih-Chieh, Lazebnik, Yuri (February 2000) Caspase Phosphorylation, Cell Death, and Species Variability. Science, 287 (5457). p. 1363.

Bellows, D. S., Chau, B. N., Lee, P., Lazebnik, Y., Burns, W. H., Hardwick, J. M. (2000) Antiapoptotic herpesvirus Bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins. Journal of Virology, 74 (11). pp. 5024-5031. ISSN 0022-538X

Faleiro, L., Lazebnik, Y. (2000) Caspases disrupt the nuclear-cytoplasmic barrier. J Cell Biol, 151 (5). pp. 951-959. ISSN 0021-9525

Zheng, T. S., Hunot, S., Kuida, K., Momoi, T., Srinivasan, A., Nicholson, D. W., Lazebnik, Y., Flavell, R. A. (2000) Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nature Medicine, 6 (11). pp. 1241-1247. ISSN 1078-8956

Svingen, P. A., Karp, J. E., Krajewski, S., Mesner, P. W., Gore, S. D., Burke, P. J., Reed, J. C., Lazebnik, Y. A., Kaufmann, S. H. (2000) Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia. Blood, 96 (12). pp. 3922-3931. ISSN 0006-4971

Duelli, D. M., Lazebnik, Y. A. (2000) Primary cells suppress oncogene-dependent apoptosis. Nature Cell Biology, 2 (11). pp. 859-862. ISSN 1465-7392

Kirsch, D. G., Doseff, A., Chau, B. N., Lim, D. S., de Souza-Pinto, N. C., Hansford, R., Kastan, M. B., Lazebnik, Y. A., Hardwick, J. M. (1999) Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. Journal of Biological Chemistry, 274 (30). pp. 21155-21161. ISSN 0021-9258

Rodriguez, J., Lazebnik, Y. (1999) Caspase-9 and APAF-1 form an active holoenzyme. Genes & Development, 13 (24). pp. 3179-3184. ISSN 0890-9369

Vaughn, D. E., Rodriguez, J., Lazebnik, Y., Joshua-Tor, L. (1999) Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling. Journal of Molecular Biology, 293 (3). pp. 439-447. ISSN 0022-2836 (Public Dataset)

Srinivasula, S. M., Ahmad, M., Guo, Y., Zhan, Y., Lazebnik, Y., Fernandes-Alnemri, T., Alnemri, E. S. (1999) Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis. Cancer Research, 59 (5). pp. 999-1002. ISSN 0008-5472

Thornberry, N. A., Lazebnik, Y. (1998) Caspases: enemies within. Science, 281 (5381). pp. 1312-1316. ISSN 0036-8075

Fearnhead, H. O., Rodriguez, J., Govek, E. E., Guo, W., Kobayashi, R., Hannon, G., Lazebnik, Y. A. (1998) Oncogene-dependent apoptosis is mediated by caspase-9. Proc Natl Acad Sci U S A, 95 (23). pp. 13664-13669. ISSN 0027-8424

Faleiro, L., Kobayashi, R., Fearnhead, H., Lazebnik, Y. (1997) Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells. Embo Journal, 16 (9). pp. 2271-2281. ISSN 0261-4189

Fearnhead, H. O., McCurrach, M. E., O'Neill, J., Zhang, K., Lowe, S. W., Lazebnik, Y. A. (1997) Oncogene-dependent apoptosis in extracts from drug-resistant cells. Genes Dev, 11 (10). pp. 1266-1276. ISSN 0890-9369

Takahashi, A., Alnemri, E. S., Lazebnik, Y. A., Fernandes-Alnemri, T., Litwack, G., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H., Earnshaw, W. C. (1996) Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. Proc Natl Acad Sci U S A, 93 (16). pp. 8395-8400. ISSN 0027-8424

Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A. (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature, 376 (6535). pp. 37-43. ISSN 0028-0836

Lazebnik, Y. A., Takahashi, A., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H., Earnshaw, W. C. (1995) Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc Natl Acad Sci U S A, 92 (20). pp. 9042-9046. ISSN 0027-8424

Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., Earnshaw, W. C. (1994) Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature, 371 (6495). pp. 346-347. ISSN 0028-0836

Lazebnik, Y. A., Cole, S., Cooke, C. A., Nelson, W. G., Earnshaw, W. C. (1993) Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis. Journal of Cell Biology, 123 (1). pp. 7-22. ISSN 0021-9525

Lazebnik, Y. A., Poletaev, A. I., Zenin, V. V. (1992) Drop-delay measurement using enzyme-coated particles. Cytometry, 13 (145159). pp. 649-652. ISSN 0196-4763

Sorkin, A., Krolenko, S., Kudrjavtceva, N., Lazebnik, J., Teslenko, L., Soderquist, A. M., Nikolsky, N. (1991) Recycling of epidermal growth factor-receptor complexes in A431 cells: identification of dual pathways. Journal of Cell Biology, 112 (1). pp. 55-63. ISSN 0021-9525

Lazebnik, Y. A., Medvedeva, N. D., Zenin, V. V. (1991) Reversible G2 block in the cell cycle of Ehrlich ascites carcinoma cells. Exp Cell Res, 195 (1). pp. 247-254. ISSN 0014-4827

Lazebnik, Y. A., Medvedeva, N. D., Zemin, V. V. (1991) [The in vivo arrest of Ehrlich ascitic carcinoma cells in the G2 phase of the cell cycle]. Tsitologiia, 33 (2). pp. 60-6. ISSN 0041-3771 (Print)0041-3771 (Linking)

Lazebnik, Y. A., Neskoromny, A. G., Konicheva, T. L. (1985) [Changes in the level of cyclic nucleotides of Ehrlich ascites carcinoma cells during progession of the tumor in vivo. Vestnik Leningradskogo Universiteta (Proceedings of the Leningrad University), 10. pp. 115-117.