Browse by CSHL Author

Lee, C. S., Lee, L. C., Yuan, T. L., Chakka, S., Fellmann, C., Lowe, S. W., Caplen, N. J., McCormick, F., Luo, J. (February 2019) MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival. Proc Natl Acad Sci U S A, 116 (10). pp. 4508-4517. ISSN 0027-8424

Yuan, T. L., Amzallag, A., Bagni, R., Yi, M., Afghani, S., Burgan, W., Fer, N., Strathern, L. A., Powell, K., Smith, B., Waters, A. M., Drubin, D., Thomson, T., Liao, R., Greninger, P., Stein, G. T., Murchie, E., Cortez, E., Egan, R. K., Procter, L., Bess, M., Cheng, K. T., Lee, C. S., Lee, L. C., Fellmann, C., Stephens, R., Luo, J., Lowe, S. W., Benes, C. H., McCormick, F. (February 2018) Differential Effector Engagement by Oncogenic KRAS. Cell Rep, 22 (7). pp. 1889-1902.

Knott, S. R., Maceli, A. R., Erard, N., Chang, K., Marran, K., Zhou, X., Gordon, A., El Demerdash, O., Wagenblast, E., Kim, S., Fellmann, C., Hannon, G. J. (December 2014) A Computational Algorithm to Predict shRNA Potency. Mol Cell, 56 (6). pp. 796-807. ISSN 1097-2765

Lito, P., Saborowski, A., Yue, J. Y., Solomon, M., Joseph, E., Fellman, C., Ohara, K., Morikami, K., Miura, T., Lucas, C., Ishii, N., Lowe, S., Rosen, N. (October 2014) Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors. Cancer Research, 74 (19). ISSN 0008-5472

Yuan, T. L., Fellmann, C., Lee, C. S., Ritchie, C. D., Thapar, V., Lee, L. C., Hsu, D. J., Grace, D., Carver, J. O., Zuber, J., Luo, J., McCormick, F., Lowe, S. W. (August 2014) Development of siRNA payloads to target KRAS-mutant cancer. Cancer Discovery, 4 (10). p. 1182. ISSN 21598274

Lito, P., Saborowski, A., Yue, J., Solomon, M., Joseph, E., Gadal, S., Saborowski, M., Kastenhuber, E., Fellmann, C., Ohara, K., Morikami, K., Miura, T., Lukacs, C., Ishii, N., Lowe, S., Rosen, N. (April 2014) Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors. Cancer Cell, 25 (5). pp. 697-710. ISSN 1878-3686 (Electronic)1535-6108 (Linking)

Tan, X., Lu, Z. J., Gao, G., Xu, Q., Hu, L., Fellmann, C., Li, M. Z., Qu, H., Lowe, S. W., Hannon, G. J., Elledge, S. J. (2012) Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy. Proceedings of the National Academy of Sciences of the United States of America, 109 (3). pp. 869-874. ISSN 00278424 (ISSN)

Dow, L. E., Premsrirut, P. K., Zuber, J., Fellmann, C., McJunkin, K., Miething, C., Park, Y., Dickins, R. A., Hannon, G. J., Lowe, S. W. (2012) A pipeline for the generation of shRNA transgenic mice. Nature Protocols, 7 (2). pp. 374-393. ISSN 17542189 (ISSN)

Zuber, J., Rappaport, A. R., Luo, W., Wang, E., Chen, C., Vaseva, A. V., Shi, J., Weissmueller, S., Fellman, C., Taylor, M. J., Weissenboeck, M., Graeber, T. G., Kogan, S. C., Vakoc, C. R., Lowe, S. W. (August 2011) An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes & Development, 25 (15). pp. 1628-1640. ISSN 0890-9369

Fellmann, C., Zuber, J., McJunkin, K., Chang, K. , Malone, C. D., Dickins, R. A., Xu, Q., Hengartner, M. O., Elledge, S. J., Hannon, G. J., Lowe, S. W. (March 2011) Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay. Molecular Cell, 41 (6). pp. 733-746. ISSN 1097-2765

Zuber, J., McJunkin, K., Fellmann, C., Dow, L. E., Taylor, M. J., Hannon, G. J., Lowe, S. W. (January 2011) Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNA. Nature Biotechnology, 29 (1). pp. 79-85.

Sendoel, A., Kohler, I., Fellmann, C., Lowe, S. W., Hengartner, M. O. (June 2010) HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase. Nature, 465 (7298). 577-U69. ISSN 0028-0836